Clene Nanomedicine
Clinical-stage biopharmaceutical company developing nanocrystal-based therapeutics for neurodegenerative diseases. Activities described on the site include nanocrystal synthesis and manufacturing, preclinical and clinical development, GMP/GLP lab operations and bioanalytical testing, regulatory filings and expanded/early access program management.
Industries
Nr. of Employees
medium (51-250)
Clene Nanomedicine
Patents
Continuous methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) resulting therefrom
US-11000042-B2
View DetailsGold-based nanocrystals for medical treatments and electrochemical manufacturing processes therefor
US-10980832-B2
View DetailsGold-based nanocrystals for medical treatments and electrochemical manufacturing processes therefor
US-10449217-B2
View DetailsContinuous methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) resulting therefrom
US-10441608-B2
View DetailsContinuous methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) resulting therefrom
US-10092007-B2
View DetailsContinuous methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) resulting therefrom
US-9743672-B2
View Details
Continuous methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) resulting therefrom
US-11000042-B2
View DetailsGold-based nanocrystals for medical treatments and electrochemical manufacturing processes therefor
US-10980832-B2
View DetailsGold-based nanocrystals for medical treatments and electrochemical manufacturing processes therefor
US-10449217-B2
View DetailsContinuous methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) resulting therefrom
US-10441608-B2
View DetailsContinuous methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) resulting therefrom
US-10092007-B2
View DetailsContinuous methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) resulting therefrom
US-9743672-B2
View DetailsProducts
Oral suspension of clean-surfaced catalytically-active gold nanocrystals
An investigational oral nanocrystal therapeutic formulated as a suspension and developed as a potential disease-modifying treatment for neurodegenerative diseases including ALS, MS and Parkinson's disease.
CNM-Au8
CNM-Au8 is a gold nanocrystal suspension currently in development as a disease-modifying treatment for people living with Amyotrophic Lateral Sclerosis, Multiple Sclerosis, and Parkinson’s Disease.
CNM-AgZn17
CNM-AgZn17 is a topical gel polymer suspension of silver and zinc ions and is being developed for treatment of infectious diseases and to accelerate wound healing.
CNM-PtAu7
CNM-PtAu7 is gold-platinum nanotherapeutic demonstrating broad-spectrum efficacy across a variety of tumor cell lines in initial in vitro research.
CNM-ZnAg
CNM-ZnAg is a proprietary zinc-silver ionic solution that has demonstrated both antiviral and antimicrobial properties.
Oral suspension of clean-surfaced catalytically-active gold nanocrystals
An investigational oral nanocrystal therapeutic formulated as a suspension and developed as a potential disease-modifying treatment for neurodegenerative diseases including ALS, MS and Parkinson's disease.
CNM-Au8
CNM-Au8 is a gold nanocrystal suspension currently in development as a disease-modifying treatment for people living with Amyotrophic Lateral Sclerosis, Multiple Sclerosis, and Parkinson’s Disease.
CNM-AgZn17
CNM-AgZn17 is a topical gel polymer suspension of silver and zinc ions and is being developed for treatment of infectious diseases and to accelerate wound healing.
CNM-PtAu7
CNM-PtAu7 is gold-platinum nanotherapeutic demonstrating broad-spectrum efficacy across a variety of tumor cell lines in initial in vitro research.
CNM-ZnAg
CNM-ZnAg is a proprietary zinc-silver ionic solution that has demonstrated both antiviral and antimicrobial properties.
Services
Management and review of individual-named and multiple-patient early access requests, eligibility assessment, protocol development for multiple-patient programs, and coordination with treating physicians and institutions.
Design and execution of Phase I-III clinical studies including protocol design, operations oversight, validated physiological and cognitive assessments, and clinical supply coordination.
Establishment and operation of GMP/GLP-compliant labs, QA oversight, and bioanalytical testing of GLP/GCP specimens to support preclinical and clinical programs.
Production procedure development, manufacturing of clean-surface nanocrystals, and manufacturing capacity planning to support clinical and early access supply.
Development and implementation of informatics systems and production control software to streamline manufacturing, QC and laboratory workflows.
Management and review of individual-named and multiple-patient early access requests, eligibility assessment, protocol development for multiple-patient programs, and coordination with treating physicians and institutions.
Design and execution of Phase I-III clinical studies including protocol design, operations oversight, validated physiological and cognitive assessments, and clinical supply coordination.
Establishment and operation of GMP/GLP-compliant labs, QA oversight, and bioanalytical testing of GLP/GCP specimens to support preclinical and clinical programs.
Production procedure development, manufacturing of clean-surface nanocrystals, and manufacturing capacity planning to support clinical and early access supply.
Development and implementation of informatics systems and production control software to streamline manufacturing, QC and laboratory workflows.
Expertise Areas
- Nanotherapeutics development
- Nanoparticle and nanocrystal manufacturing
- GxP-compliant laboratory operations
- Preclinical translational research and animal models
Key Technologies
- Nanocrystal-based therapeutics
- Nanoparticle synthesis and surface engineering
- Clean-surface catalytically-active gold nanocrystals
- GxP laboratory informatics (LIMS)