Civi Biopharma, Inc.


CiVi Biopharma is a clinical-stage biotechnology company focused on creating novel cardiovascular and metabolic therapies. The company develops assets in various stages of development, including intravenous iloprost for severe frostbite and oral PCSK9 inhibitors for cardiovascular disease. Founded in 2017 and headquartered in Chevy Chase, MD, CiVi Biopharma aims to deliver meaningful value to patients through innovative treatments.

Industries

biotechnology
clinical-trials
pharmaceutical

Nr. of Employees

small (1-50)

Civi Biopharma, Inc.

5425 Wisconsin Avenue, 6th Floor, Chevy Chase, MD 20815


Patents

Oral delivery of antisense conjugates targeting PCSK9

US-12291708-B2

View Details

Products

CiVi 008

A third-generation antisense oligonucleotide designed to inhibit PCSK9 mRNA as an oral treatment to lower LDL-cholesterol and prevent atherosclerotic cardiovascular disease.

CiVi 030

An intravenous formulation of iloprost, developed as a vasoactive, platelet-inhibiting agent with anti-inflammatory and anti-fibrotic properties for treatment of severe frostbite and related vascular conditions.

Expertise Areas

  • Antisense oligonucleotide therapeutics
  • Oral drug formulation for oligonucleotides
  • Preclinical pharmacology and toxicology (non-human primate)
  • Clinical trial management (Phase I–III)
  • Show More (4)

Key Technologies

  • Antisense oligonucleotides
  • RNA-targeted therapeutics
  • Oral drug delivery formulation
  • Intravenous formulation development
  • Show More (4)

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