Centrus Diagnostics
Develops wearable, cuffless sensor platforms and closed‑loop therapies to improve diagnosis and treatment of hypertension, heart failure, and atrial fibrillation. Core efforts focus on continuous, hospital‑grade blood pressure measurement using photoplethysmography (PPG), wearable electrocardiographic acquisition, signal processing and AI algorithms, and integration of real‑time blood pressure data with pacemaker control in a secure wireless ecosystem. Activities span benchtop prototyping, preclinical testing, clinical trials, and regulatory validation.
Industries
Nr. of Employees
small (1-50)
Centrus Diagnostics
Products
Wearable cuffless blood pressure smartwatch — snapshot mode (5–10s)
Wrist‑worn device designed to provide frequent snapshot blood pressure readings (every 5–10 seconds) and calibrated against cuff devices for reduced drift; targeted for medical‑grade accuracy and regulatory clearance.
Wearable cuffless blood pressure smartwatch — continuous mode
Integrated wearable intended for truly continuous blood pressure monitoring with calibration and position correction for continuous trend analysis.
Closed‑loop pacemaker control system (algorithm and bedside module)
Software and module that process real‑time blood pressure data, calculate optimal pacing rates, provide patient interaction prompts, and wirelessly transmit encrypted pacing commands to a dual‑chamber pacemaker.
Field device for clinical testing
Released device intended for clinical testing and validation of wearable blood pressure measurement performance.
Wearable cuffless blood pressure smartwatch — snapshot mode (5–10s)
Wrist‑worn device designed to provide frequent snapshot blood pressure readings (every 5–10 seconds) and calibrated against cuff devices for reduced drift; targeted for medical‑grade accuracy and regulatory clearance.
Wearable cuffless blood pressure smartwatch — continuous mode
Integrated wearable intended for truly continuous blood pressure monitoring with calibration and position correction for continuous trend analysis.
Closed‑loop pacemaker control system (algorithm and bedside module)
Software and module that process real‑time blood pressure data, calculate optimal pacing rates, provide patient interaction prompts, and wirelessly transmit encrypted pacing commands to a dual‑chamber pacemaker.
Field device for clinical testing
Released device intended for clinical testing and validation of wearable blood pressure measurement performance.
Services
Prototype engineering and benchtop development
Bench engineering, alpha production and prototype refinement for wearable blood pressure and closed‑loop control devices.
Preclinical and animal testing
Execution of animal model studies to evaluate physiologic responses and device safety.
Clinical study design and trial execution
Design and conduct of retrospective and prospective clinical trials, IRB coordination, and multi‑site early feasibility studies.
Regulatory testing and 510(k) preparedness
Regulatory test planning and execution in support of FDA 510(k) and other market clearances (e.g., CE, CDSCO/DCGI).
Signal processing and AI algorithm development
Development of PPG/ECG signal processing, motion compensation, skin‑tone robustness, and AI models for autonomous control.
Integration with implantable cardiac devices
Technical integration and secure wireless communication between external monitoring devices and implanted pacemaker systems for closed‑loop therapy.
Prototype engineering and benchtop development
Bench engineering, alpha production and prototype refinement for wearable blood pressure and closed‑loop control devices.
Preclinical and animal testing
Execution of animal model studies to evaluate physiologic responses and device safety.
Clinical study design and trial execution
Design and conduct of retrospective and prospective clinical trials, IRB coordination, and multi‑site early feasibility studies.
Regulatory testing and 510(k) preparedness
Regulatory test planning and execution in support of FDA 510(k) and other market clearances (e.g., CE, CDSCO/DCGI).
Signal processing and AI algorithm development
Development of PPG/ECG signal processing, motion compensation, skin‑tone robustness, and AI models for autonomous control.
Integration with implantable cardiac devices
Technical integration and secure wireless communication between external monitoring devices and implanted pacemaker systems for closed‑loop therapy.
Expertise Areas
- Wearable medical device development
- Cuffless continuous blood pressure monitoring
- Closed‑loop pacemaker therapy development
- Clinical trial design and execution
Key Technologies
- Photoplethysmography (PPG)
- Electrocardiography (ECG/EKG)
- Bluetooth wireless communication
- AI / machine learning algorithms