Center for Vaccine Research


The Center for Vaccine Research (CVR) at the University of Pittsburgh is dedicated to advancing research in infectious diseases, vaccine development, and therapeutics. It houses state-of-the-art facilities including the Regional Biocontainment Laboratory and Biomedical Science Tower 3, and collaborates with various disciplines to improve global health through innovative biomedical research and vaccine development.

Industries

biotechnology
life-science
medical

Nr. of Employees

small (1-50)

Center for Vaccine Research

9014 Biomedical Science Tower 3, 3501 Fifth Avenue, Pittsburgh, PA 15261


Services

Provision of enhanced BSL-3 and ABSL-3 laboratory space for research projects, including containment infrastructure and on-site technical support for high-risk pathogen work.

Design and conduct of controlled aerosol exposures in animal models using automated aerosol generation and control systems with trained aerobiology personnel.

Preclinical PET/CT and CT imaging acquisition and interpretation for small animals and nonhuman primates, with image analysis support.

Services for nucleic acid extraction, sequencing, SNP/genotyping assays, gene expression analysis, protein profiling, proteomic identification and mass-spectrometry-based characterization.

Custom synthetic peptide production with purification and mass-spectrometry verification, including options for chemical modifications and production documentation for clinical use.

Analytical support for study design and downstream data analysis across genomic and proteomic datasets, including consultation on patient accrual algorithms and multivariable selection for clinical studies.

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Expertise Areas

  • Vaccine development and translational research
  • High-containment infectious disease research (BSL-3/ABSL-3)
  • Preclinical animal models and aerobiology challenge models
  • Genomics and proteomics analysis
  • Show More (5)

Key Technologies

  • BSL-3 and ABSL-3 containment systems
  • Aerosol exposure systems and automated aerosol control
  • Flow cytometry and cell sorting
  • Multiplex immunoassays
  • Show More (8)

News & Updates

CVR Seminar Series

Weekly seminars featuring leading scientists in vaccine research and infectious diseases.

COVID-19 Vaccine Trials

Participation in vaccine trials and research related to COVID-19.

Research in Emerging Infectious Diseases

Ongoing research projects on emerging infectious diseases and biodefense.

Pitt CVR's Role in Pandemic Preparedness

An article discussing the contributions of the CVR to pandemic preparedness and vaccine development.

Advances in Vaccine Technology at Pitt

Recent breakthroughs in vaccine technology achieved by CVR researchers.

CVR's Biocontainment Facilities

Details about the state-of-the-art biocontainment laboratories at CVR.

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