Cellular Technology Limited ‰ÛÓ CTL

A library of genetically and immunologically characterized white blood cells cryopreserved to maintain full functionality, with hundreds of aliquots from each subject.

Human PBMC isolated from leukopacks/lymphopacks and frozen in CTL-CryoABC™ serum-free freezing medium, designed for T cell and B cell monitoring.

Visual light and fluorescent analyzers featuring sophisticated software for up to eight-color analysis and automated spot recognition and gating.

This model enables advanced three-color FluoroSpot work, in addition to single- and double-color enzymatic ELISPOT analysis using white light, as well as high-throughput counting of live and dead PBMC.

Cryopreserved peripheral blood mononuclear cells (PBMC) characterized for peptide and protein antigen reactivity on the frequency of T cells that secrete IFN-γ, IL-2, IL-4, IL-5, IL-13, and IL-17.

The S6 Flex M2 is a dedicated 4-color FluoroSpot reader that supports ELISPOT and FluoroSpot testing with high-throughput PBMC viability counting, viral neutralization assays, and cell-mediated cytotoxicity assays.

Human Peripheral Blood Mononuclear Cells (PBMC) isolated from leukopacks, processed, pooled and frozen in CTL-CryoABC serum-free freezing medium.

Positive controls designed for antigen-driven activation of CD4+ and/or CD8+ T cell memory to assess the functional fitness and performance of PBMCs in T cell assays.

Comprehensive pyrogen testing services and implementation support utilizing cryopreserved peripheral blood mononuclear cells (PBMC) and IL-6 ELISA to detect microbial contaminants and non-endotoxin pyrogens in compliance with European Pharmacopoeia standards.

Reference PBMC with established high-resolution HLA-type and defined CD4 and CD8 cell reactivity to various antigens.

An adaptation of traditional enzymatic ELISPOT detection systems utilizing fluorochrome-conjugated detection antibodies for simultaneous multiplexed detection of secreted cytokines or antibodies.

8-donor configuration kit for European Pharmacopoeia compliant in-vitro pyrogen testing, complete with cryopreserved pooled PBMC, IL-6 ELISA, and reagents.

ImmunoSpot analyzer model optimized for single-color and FluoroSpot applications with fixed lens optics and 10 megapixel resolution.

Proficiency testing service provided by CTL to verify ELISPOT/FluoroSpot assay proficiency using pre-characterized cryopreserved human PBMC samples, antigens, reagents, and protocols.

State-of-the-art ELISPOT assays for the detection, measurement, and functional analysis of immune cells secreting specific signature proteins such as antibodies or cytokines.

Serum-free media for low background and high signal for consistent performance in ImmunoSpot® assays.

A positive control reagent consisting of a pool of protein antigens derived from Cytomegalo-, Influenza, and Parainfluenza viruses used for assessing the functionality of CD4+ T cells and antigen-presenting cells (APCs).

Cryopreserved pooled PBMC from eight healthy donors fulfilling quality criteria according to EP 2.6.30 for MAT testing.

Cryopreserved pooled PBMC from four healthy donors fulfilling quality criteria according to EP 2.6.30 for MAT testing.

Positive controls for antigen-driven activation of CD4+ and CD8+ T cells.

Enables European Pharmacopoeia compliant in-vitro pyrogen testing including endotoxin and three non-endotoxin pyrogen positive controls alongside pooled PBMC and IL-6 ELISA.

Comprehensive alternative to the antiquated Rabbit Pyrogen Test and the Limulus Amebocyte Lysate assay.

Serum-free media permitting loss-free cryopreservation and optimized testing of PBMC, eliminating serum variables.

Commercial software platform designed for objective, scientifically validated counting and analysis of ELISPOT assays, featuring automated algorithms like AutoGate™, SmartCount™, and SmartSpot® for precise spot size and density distribution analysis.

Formulated for direct ex vivo testing of PBMC in cellular cytokine assays (ELISPOT, ELISA, CBA, CPA), showing equal or better performance than pre-screened, non-mitogenic serum batches. It provides a physiologically complete and nutritionally balanced environment for PBMC.

Serum-free freezing media kit for cryopreservation of freshly-isolated PBMC, ensuring higher than 90% viability and unimpaired PBMC function in T cell cytokine recall assays.

Analyzer equipped with the CTL Cell Counting Software Suite for cell imaging, counting, and analysis.

Entry-level automated analyzer supporting 96 and 384-well formats with integrated barcode reading.

Compact entry-level S6 analyzer for single-color ELISPOT applications in 96-well formats.

An optimized FluoroSpot assay designed to reliably detect and measure human IFN-γ, IL-2, IL-5, and IL-17 secretions by stimulated effector cells at frequencies as low as one in a million.

Software suite supporting image-analysis of neutralization assays, colony counting, and more of any well format in a high-throughput manner.

An optimized FluoroSpot assay that reliably detects and measures human and NHP IFN-γ, IL-2, TNF-α, and Perforin secretions by stimulated effector cells.

A software suite enabled by CTL's fluorescence-capable ImmunoSpot Readers that performs live, dead, and apoptotic PBMC counting on the fly in various hemocytometer formats and 96-well plates.

Serum-free freezing media kit for cryopreservation of freshly-isolated PBMC.

Pooled PBMC from 8 healthy donors, 20 million cells per vial.

Pooled PBMC from 4 healthy donors, 10 million cells per vial.

An optimized FluoroSpot assay designed to reliably detect and measure human IFN-γ, IL-10, IL-2, and TNF-α secretions by stimulated effector cells at single-cell resolution.

A high-throughput software suite designed for automated colony counting and neutralization assays, supporting any well format from 384-well plates down to Petri dishes and square agar slabs.

Capture kit for human IFN-γ/IL-2/IL-5 three-color FluoroSpot assay including diluents, serum-free assay medium, and capture antibodies with low autofluorescence PVDF-membrane plates.

An optimized FluoroSpot assay that reliably detects and measures human IFN-γ, IL-2, IL-5, and Granzyme B secretions by stimulated effector cells.

An optimized FluoroSpot assay that reliably detects and measures human IFN-γ, IL-2 and IL-17 secretions by stimulated effector cells in frequencies as low as one in a million.

Media solutions for PBMC thawing, washing, and testing.

Facilitates detection of rare antigen-specific Th1, Th2, and Th17 memory cells.

Precoated capture kit for human IFN-γ/IL-2/IL-5/Granzyme B Four-Color FluoroSpot assay.

Solutions to allow scientists to preserve their own fully-functional PBMC samples.

Three selected protein antigens from the Cytomegalo-, Influenza, and Parainfluenza viruses at 1mg/ml of the protein pool serving as a positive control for CD4 cell activation.

An optimized ELISPOT assay that reliably detects and measures human IFN-γ and IL-4 secretions by stimulated effector cells in frequencies as low as one in a million.

High-resolution microplate analyzer supporting dense well formats up to 1536 wells and Terasaki plates.

Capture kit component for the Human IFN-γ/IL-2/TNF-α/Perforin Four-Color FluoroSpot assay.

Detection kit for Granzyme B in FluoroSpot assay.

Single-color enzymatic and fluorescent detection kits available for human, NHP, mouse, pig, and rat with various cytokine targets.

Optimized ELISPOT assay designed to reliably detect and measure human IFN-̳ and IL-6 secretions by stimulated effector cells in frequencies as low as one in a million.

Precoated capture kit component for the Human IFN-γ/IL-2/IL-5/IL-17 Four-Color FluoroSpot assay.

An optimized ELISPOT assay designed to reliably detect and measure human and some NHP IFN-γ secretions by stimulated effector cells in frequencies as low as one in a million, featuring a directly conjugated detection antibody for faster results.

An optimized ELISPOT assay that reliably detects and measures human and some NHP IFN-γ and IL-17 secretions by stimulated effector cells in frequencies as low as one in a million.

32 HLA class I-restricted T cell epitopes from Cytomegalovirus, Epstein-Barr virus, and Influenza virus. Positive control for CD8 cell activation.

An optimized ELISPOT assay that reliably detects and measures human IFN-γ and IL-22 secretions by stimulated effector cells in frequencies as low as one in a million.

Specialized fluorescent kits combining cytokine and antibody detection profiles for comprehensive cell analysis.

Advanced multiplex fluorescent kits for detecting up to four distinct analytes simultaneously in T and B cells.

A universal CD8+ T cell positive control comprised of 124 immune-dominant epitopes of endemic viruses, designed to work across a broad range of HLA class I alleles and diverse human populations.

Precoated capture kit component for Human IFN-γ/IL-10/IL-2/TNF-α FluoroSpot assay.

Detection kit for IL-2 in FluoroSpot assays.

Kits containing two substrates or fluorescent conjugates with separate emission spectrums to detect two cytokines simultaneously.

Multiplex fluorescent kits designed to detect three distinct cytokine secretions simultaneously.

A buffered, ready-to-use solution for the enumeration of live and dead eukaryotic cells including PBMC, incorporating CTL-LDC ™ Reagent and disposable hemocytometers.

Fluorescent dye reagent used to distinguish between live and dead cells for accurate cell counting.

Detection kit for IL-10 in FluoroSpot assays.

Detection kit for IL-5 in FluoroSpot assays.

Detection kit for IL-17 in FluoroSpot assays.

Stabilizes PBMC during thawing and prevents cell loss through aggregation. Contains DNAse, amino acids, vitamins, inorganic salts, and human serum albumin to provide a nutritionally complete environment.

Specially formulated, nutrient-rich serum-free 10x supplement for PBMC, designed to provide a nutritionally complete and balanced environment for maximizing PBMC survival, viability, and functionality during washing and handling.

CTL SpotMap solutions for analyzing data.

Robotic arm plate loader extension fitting any ImmunoSpot Reader, capable of loading up to 400 plates in a single run.

An easy, accurate, high-throughput-suitable method for determining cell viability. Includes CTL-LDC Reagent and fifty disposable, 2-chamber hemocytometer slides.

An easy, accurate, high-throughput-suitable method for determining cell viability.

Detection kit component for human IgG1 in FluoroSpot assays.

Detection kit component for human IgG3 in FluoroSpot assays.

Macro imaging system designed for Petri dishes and high-throughput automation compatibility.

Detection kit for Human IgG.

Detection kit component for human IgG4 in FluoroSpot assays.

Plasma matching the characterized ePBMC, available in a 0.5ml aliquot.

Detection kit for Human IgM.

Detection kit for Human IgE.

Detection kit for Human IgA.

Specialized supplement used to prevent cell aggregation during the processing of human PBMC.

10ml aliquot of plasma matching the pooled PBMC.

0.5ml aliquot of plasma matching the pooled PBMC.

CTL Readers can scan 4 Histo Microarray slides in one run for applications such as counting flu virus infected cells in cat lung biopsy.

Automated plate stacker accessory for S6 analyzers with a capacity of up to 50 plates.

Robotic plate handling system with a capacity of up to 400 plates for fully automated integration.

Telecentric macro imaging system for high-precision optical capture across medium-sized Petri dishes.

Advanced plate stacker supporting multi-format plates including lids-on processing.