Cellinfinity Bio
Cellinfinity Bio is dedicated to harnessing evolution for genetic reprogramming of immune cells in the body, providing innovative solutions to overcome barriers in solid tumor cell therapy. They focus on evolving immune cells to improve tumor infiltration, potency, and persistence, using principles of evolution such as scFv, vector, CAR, and genomic evolution.
Industries
Nr. of Employees
small (1-50)
Cellinfinity Bio
101 College Street, Suite 210, New Haven, CT 06510
Products
CLASH™
A platform that uses machine learning to edit up to 20,000 genes in cells, enabling precise and replicable site-specific edits to discover gene enhancements for cell therapy.
HYPERBOOSTS
Novel gain-of-function genes discovered using the CLASH™ platform to enhance the performance of immune cells in cell therapy.
ENDOMODS
Novel loss-of-function genes identified through the CLASH™ platform to improve the efficacy of immune cells in cell therapy.
OPTI-CARS
Novel modifications to CAR design discovered using the CLASH™ platform to enhance the effectiveness of CAR-T and CAR-NK cells.
Supercharged Cell Therapy™
Engineered CAR-T and CAR-NK cells programmed with multiple gene enhancements to increase potency, persistence, penetration, and memory for better efficacy against solid tumors.
CLASH™
A platform that uses machine learning to edit up to 20,000 genes in cells, enabling precise and replicable site-specific edits to discover gene enhancements for cell therapy.
HYPERBOOSTS
Novel gain-of-function genes discovered using the CLASH™ platform to enhance the performance of immune cells in cell therapy.
ENDOMODS
Novel loss-of-function genes identified through the CLASH™ platform to improve the efficacy of immune cells in cell therapy.
OPTI-CARS
Novel modifications to CAR design discovered using the CLASH™ platform to enhance the effectiveness of CAR-T and CAR-NK cells.
Supercharged Cell Therapy™
Engineered CAR-T and CAR-NK cells programmed with multiple gene enhancements to increase potency, persistence, penetration, and memory for better efficacy against solid tumors.
Services
Platform for discovery and engineering of antibody fragments, delivery vectors, CAR constructs, and genetic enhancements intended to reprogram patient immune cells in situ for treatment of solid tumors.
Platform for discovery and engineering of antibody fragments, delivery vectors, CAR constructs, and genetic enhancements intended to reprogram patient immune cells in situ for treatment of solid tumors.
Expertise Areas
- In vivo cell therapy development
- Cell engineering and genetic programming
- Antibody-fragment discovery and engineering
- Vector design and in vivo delivery
Key Technologies
- In vivo gene-delivery vectors
- Directed evolution / evolutionary engineering
- scFv (single-chain variable fragment) engineering
- Chimeric antigen receptor (CAR) engineering