Castle Institutional Review Board


Sabai IRB Services operates two premier institutional review boards, Castle IRB and Alpha IRB, dedicated to protecting the rights, safety, and welfare of human research participants. They offer comprehensive IRB review services, utilize advanced web portal systems for study management, and are committed to compliance with US regulations and accreditation standards. Their mission is to support researchers through quality, timeliness, and subject matter expertise, ensuring ethical and regulatory adherence in all research activities.

Industries

clinical-trials
consumer-research
health-care

Nr. of Employees

small (1-50)

Castle Institutional Review Board

16150 Main Circle Dr, Suite #100, Chesterfield, MO 63017


Products

IRB submission form and guidance package

Standardized downloadable application forms and guidance documents for sponsor/CRO study applications, site submissions, continuing review, protocol deviation reporting, serious adverse event reporting and other submission types.

Short-form consent templates and translations

Short-form consent documents and certificates of translation accuracy available in multiple languages for use when full written consent cannot be obtained in the subject's language.


Services

Ethics and regulatory review services for human subjects research across single-site, multi-site, device, pharmaceutical, biotech, social-behavioral, registry and investigator-initiated studies; includes initial and continuing review, amendments, exempt determinations and safety reporting.

Assistance with portal account creation, user support, portal demos, and guidance for completing online submissions and retrieving approval documents.

Registration access for human subjects and Good Clinical Practice training and provision of participant-facing information and FAQs.

Expertise Areas

  • IRB management and ethical review
  • Regulatory compliance for human subjects research
  • Multi-site study coordination
  • Single-patient expanded access review
  • Show More (4)

Key Technologies

  • Web-based IRB management portals
  • Electronic signature systems (21 CFR Part 11 compliant)
  • Online document management and retrieval
  • Secure user authentication and account management
  • Show More (4)

News & Updates

Schedule of Alpha IRB full board meetings and submission deadlines for 2025.

AAHRPP Accreditation for Both IRBs

Both Castle IRB and Alpha IRB operate with AAHRPP accreditation, ensuring high standards in research protections.

FDA/OHRP Registration of IRBs

Castle IRB and Alpha IRB are registered with the FDA and OHRP, complying with federal regulations.


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