Cardiovascular Clinical Sciences
A specialized contract research organization focused on cardiovascular drug and device development. CCS combines academic clinical leadership and CRO operations to provide trial design, biostatistics, data management, core imaging laboratory services, pharmacovigilance, and global site operations for Phase I–III studies.
Industries
Nr. of Employees
small (1-50)
Cardiovascular Clinical Sciences
Boston, Massachusetts, United States, North America
Products
Clinical Research Services
Provides comprehensive support for cardiovascular clinical trials from Phase I to Phase III, including study design, management, operations, data management, and safety monitoring.
Cardiovascular Core Laboratory Services
Offers integrated cardiovascular imaging and hemodynamic core lab services including protocol development, site selection, image processing, and endpoint analysis for clinical trials.
Clinical Research Services
Provides comprehensive support for cardiovascular clinical trials from Phase I to Phase III, including study design, management, operations, data management, and safety monitoring.
Cardiovascular Core Laboratory Services
Offers integrated cardiovascular imaging and hemodynamic core lab services including protocol development, site selection, image processing, and endpoint analysis for clinical trials.
Services
Consultancy and execution of clinical development strategy, integrated product development plans, literature reviews, expert interviews, and risk management plans from concept to market.
Clinical operations covering Phase I–III trials including site management, monitoring, enrollment support, and operational plans.
Endpoint acquisition and analysis services including imaging protocol development, image processing, centralized reading, and variability analysis to produce submission-ready endpoint data.
In-house Ph.D.-level biostatistics for power and time-cost analyses, adaptive design support, statistical analysis plans, interim analyses, and CDISC dataset production.
Database build, data collection standardization, ongoing cleaning and query resolution, and delivery of submission-ready datasets and electronic TMF support.
Customized analytics and reporting across startup, enrollment, data integrity, and quality tolerance metrics, with central monitoring and issue escalation processes.
Consultancy and execution of clinical development strategy, integrated product development plans, literature reviews, expert interviews, and risk management plans from concept to market.
Clinical operations covering Phase I–III trials including site management, monitoring, enrollment support, and operational plans.
Endpoint acquisition and analysis services including imaging protocol development, image processing, centralized reading, and variability analysis to produce submission-ready endpoint data.
In-house Ph.D.-level biostatistics for power and time-cost analyses, adaptive design support, statistical analysis plans, interim analyses, and CDISC dataset production.
Database build, data collection standardization, ongoing cleaning and query resolution, and delivery of submission-ready datasets and electronic TMF support.
Customized analytics and reporting across startup, enrollment, data integrity, and quality tolerance metrics, with central monitoring and issue escalation processes.
Expertise Areas
- Cardiovascular clinical trial management
- Cardiovascular imaging core laboratory operations
- Biostatistics and adaptive trial design
- Clinical data management and CDISC dataset production
Key Technologies
- Adaptive trial simulations
- Risk-based and centralized remote monitoring
- CDISC SDTM and ADaM dataset standards
- SAS programming for clinical analysis
News & Updates
Publication listed as a notable work associated with CCS clinical leadership (Konstam MA et al.).
Guideline update noted among notable publications associated with CCS leadership.
Recent publication listed for CCS scientific leadership (Konstam MA et al.).
Recent publication listed for CCS clinical leadership (Udelson JE et al.).
Founded in 1997 with multi-decade experience supporting single-center Phase I studies to 5,000-patient pivotal trials.
Core lab faculty reported as authors on over 900 publications with more than 25,000 citations; core lab services in operation since 2004.
Publication listed as a notable work associated with CCS clinical leadership (Konstam MA et al.).
Guideline update noted among notable publications associated with CCS leadership.
Recent publication listed for CCS scientific leadership (Konstam MA et al.).
Recent publication listed for CCS clinical leadership (Udelson JE et al.).
Founded in 1997 with multi-decade experience supporting single-center Phase I studies to 5,000-patient pivotal trials.
Core lab faculty reported as authors on over 900 publications with more than 25,000 citations; core lab services in operation since 2004.