BRAINBox Solutions
BRAINBox Solutions is dedicated to developing innovative, AI-enabled, multi-modality diagnostic and prognostic tools for traumatic brain injury (TBI), including concussion. Their approach combines blood biomarkers, neurocognitive testing, and AI algorithms to provide objective diagnosis and prognosis, aiming to establish a new standard in TBI care.
Industries
Nr. of Employees
small (1-50)
BRAINBox Solutions
Patents
Protein biomarker indicators of neurological injury and/or disease and methods of use thereof
US-12736547-B2
View DetailsBiomarker levels and neuroimaging for detecting, monitoring and treating brain injury or trauma
US-12461112-B2
View DetailsCirculating biomarker levels for diagnosis and risk-stratification of traumatic brain injury
US-12265091-B2
View DetailsProtein biomarker indicators of neurological injury and/or disease and methods of use thereof
US-11988676-B2
View Details
Protein biomarker indicators of neurological injury and/or disease and methods of use thereof
US-12736547-B2
View DetailsBiomarker levels and neuroimaging for detecting, monitoring and treating brain injury or trauma
US-12461112-B2
View DetailsCirculating biomarker levels for diagnosis and risk-stratification of traumatic brain injury
US-12265091-B2
View DetailsProtein biomarker indicators of neurological injury and/or disease and methods of use thereof
US-11988676-B2
View DetailsProducts
Multi‑modality diagnostic and prognostic test for acute brain injury
A system combining a multiplex blood biomarker panel, rapid point‑of‑care quantitative measurement, tablet‑delivered neurocognitive testing, and AI/ML algorithms to generate a single objective diagnostic score and a prognosis report indicating likelihood of persistent symptoms.
BRAINBox TBI™ concussion diagnostic and prognostic test
A multi-modal test combining clinical data, neurocognitive testing, symptom reporting, and blood-based biomarkers with proprietary AI algorithms to generate an objective score for concussion diagnosis up to 96 hours from injury and prognosis for symptoms at 30 days to three months.
BrainBox Solutions multi-modality mTBI test
A multi-modality product combining point-of-care measurement of protein biomarkers linked to mild traumatic brain injury (mTBI) with additional tests like cognitive assessments to diagnose and monitor mTBI cases and determine patient risk of longer-term effects.
BRAINBox point of care device
A device that runs a panel of TBI-associated blood-based biomarkers using a small blood sample, analyzed with a neurocognitive assessment to provide a BRAINBox TBI score.
BRAINBox Geriatrics
A multi-modal system for the diagnosis and prognosis of occult mild traumatic brain injury (mTBI or concussion) and cognitive impairment in elderly patients, integrating blood biomarkers with functional tests for rapid bedside diagnosis and prognosis.
Multi‑modality diagnostic and prognostic test for acute brain injury
A system combining a multiplex blood biomarker panel, rapid point‑of‑care quantitative measurement, tablet‑delivered neurocognitive testing, and AI/ML algorithms to generate a single objective diagnostic score and a prognosis report indicating likelihood of persistent symptoms.
BRAINBox TBI™ concussion diagnostic and prognostic test
A multi-modal test combining clinical data, neurocognitive testing, symptom reporting, and blood-based biomarkers with proprietary AI algorithms to generate an objective score for concussion diagnosis up to 96 hours from injury and prognosis for symptoms at 30 days to three months.
BrainBox Solutions multi-modality mTBI test
A multi-modality product combining point-of-care measurement of protein biomarkers linked to mild traumatic brain injury (mTBI) with additional tests like cognitive assessments to diagnose and monitor mTBI cases and determine patient risk of longer-term effects.
BRAINBox point of care device
A device that runs a panel of TBI-associated blood-based biomarkers using a small blood sample, analyzed with a neurocognitive assessment to provide a BRAINBox TBI score.
BRAINBox Geriatrics
A multi-modal system for the diagnosis and prognosis of occult mild traumatic brain injury (mTBI or concussion) and cognitive impairment in elderly patients, integrating blood biomarkers with functional tests for rapid bedside diagnosis and prognosis.
Services
Design and execution support for multi‑site clinical studies evaluating biomarker and neurocognitive test performance; collaborations with hospitals, academic centers and sports organizations for population‑specific studies.
Implementation support to deliver biomarker tests on bedside instruments and standard laboratory analyzers, including assay format and workflow integration.
Design and execution support for multi‑site clinical studies evaluating biomarker and neurocognitive test performance; collaborations with hospitals, academic centers and sports organizations for population‑specific studies.
Implementation support to deliver biomarker tests on bedside instruments and standard laboratory analyzers, including assay format and workflow integration.
Expertise Areas
- Clinical trial management (multi‑site, multi‑national)
- Biomarker discovery and analytical validation
- Point‑of‑care diagnostic development
- Digital neurocognitive assessment and software integration
Key Technologies
- Multiplex fluorescent immunoassays
- Protein biomarker panels (examples: GFAP, NSE, Neurogranin, BDNF, Aldolase C)
- Point‑of‑care testing (rapid quantitative assays)
- Tablet‑based neurocognitive testing