Biological Mimetics
Biological Mimetics, Inc. (BMI) is a leading biomedical company founded in 1996, dedicated to innovating in vaccine development and diagnostics. The company integrates biology and engineering to identify and prevent global infections, employing proprietary platforms such as Immune Refocusing Technology (IRT), ultra UVC irradiation, and FAST chip diagnostics. BMI's mission is to improve public health by combating resistant and emerging diseases in human and veterinary medicine, with a focus on underrepresented targets including viral, bacterial, and parasitic pathogens.
Industries
Nr. of Employees
small (1-50)
Biological Mimetics
Frederick, Maryland, United States, North America
Patents
Irradiation-inactivated poliovirus, compositions including the same, and methods of preparation
US-12042533-B2
View Details
Irradiation-inactivated poliovirus, compositions including the same, and methods of preparation
US-12042533-B2
View DetailsProducts
Multi-chamber disposable microfluidic diagnostic device (instrument-free)
A disposable, multi-chamber microfluidic device preloaded with reagents that enables sample disruption, isothermal amplification, and CRISPR-based optical readout without electrical power or pipettes.
UVC inactivation vaccine platform with MDP formulation
Inactivated vaccine approach that complexes pathogens with an MDP formulation prior to UVC irradiation to produce inactivated immunogens intended for vaccine development.
Ellipsometry-based rapid bacterial detection assay
A rapid diagnostic assay using ellipsometry-based sensing to detect and characterize bacterial infections for rapid clinical decision-making.
FAST
A convenient multi-chambered diagnostic tool pre-loaded with reaction components for simple, instrument-free step-wise performance of CRISPR diagnostics. Integrates isothermal RPA amplification and CRISPR cleavage for sensitive nucleic acid detection, suitable for low-income countries.
FAST (Funnel-adapted sensing tube)
A multi-chambered device that simplifies genotype-specific diagnostics, adapted for multiple pathogens for instrument-free electricity-free diagnostics. It is a simple, portable, and low-cost microfluidic system developed as an integrated, power-free, and pipette-free biosensor for viral nucleic acids.
ultraIPV
A technology platform where pathogens are complexed with a manganese-decapeptide-phosphate (MDP) and then exposed to UV light, offering a quick, easy, and reproducible process that lowers manufacturing costs. Adapted from radiation-resistant bacteria such as Deinococcus radiodurans.
Multi-chamber disposable microfluidic diagnostic device (instrument-free)
A disposable, multi-chamber microfluidic device preloaded with reagents that enables sample disruption, isothermal amplification, and CRISPR-based optical readout without electrical power or pipettes.
UVC inactivation vaccine platform with MDP formulation
Inactivated vaccine approach that complexes pathogens with an MDP formulation prior to UVC irradiation to produce inactivated immunogens intended for vaccine development.
Ellipsometry-based rapid bacterial detection assay
A rapid diagnostic assay using ellipsometry-based sensing to detect and characterize bacterial infections for rapid clinical decision-making.
FAST
A convenient multi-chambered diagnostic tool pre-loaded with reaction components for simple, instrument-free step-wise performance of CRISPR diagnostics. Integrates isothermal RPA amplification and CRISPR cleavage for sensitive nucleic acid detection, suitable for low-income countries.
FAST (Funnel-adapted sensing tube)
A multi-chambered device that simplifies genotype-specific diagnostics, adapted for multiple pathogens for instrument-free electricity-free diagnostics. It is a simple, portable, and low-cost microfluidic system developed as an integrated, power-free, and pipette-free biosensor for viral nucleic acids.
ultraIPV
A technology platform where pathogens are complexed with a manganese-decapeptide-phosphate (MDP) and then exposed to UV light, offering a quick, easy, and reproducible process that lowers manufacturing costs. Adapted from radiation-resistant bacteria such as Deinococcus radiodurans.
Services
Coordination and execution of grant-funded research programs, partnerships with academic and government collaborators, milestone reporting, and grant administration.
Production of GLP/GMP-like lots for animal safety and efficacy studies and preparation of regulatory documentation to support IND submissions.
Development of low-cost, instrument-free diagnostic prototypes integrating isothermal amplification and CRISPR detection, and coordination of beta-testing with collaborators and blinded sample providers.
Coordination and execution of grant-funded research programs, partnerships with academic and government collaborators, milestone reporting, and grant administration.
Production of GLP/GMP-like lots for animal safety and efficacy studies and preparation of regulatory documentation to support IND submissions.
Development of low-cost, instrument-free diagnostic prototypes integrating isothermal amplification and CRISPR detection, and coordination of beta-testing with collaborators and blinded sample providers.
Expertise Areas
- Vaccine design and development
- Point-of-care nucleic acid diagnostics
- Computational immunology and epitope prediction
- Biosensor engineering and nanoparticle-enabled sensing
Key Technologies
- CRISPR-based diagnostics (Cas12a/Cas13a)
- Isothermal amplification (RPA)
- Microfluidic multi-chamber disposable chips
- UVC inactivation with manganese-decapeptide-phosphate (MDP)
News & Updates
Development of ultra IPV Vaccine for Polio
Progress towards IND enabling studies for a gamma radiation-inactivated Sabin-based polio vaccine.
Vaccine for Acinetobacter Baumannii
Finalization of a lead candidate using UVC inactivation tested at WRAIR.
Universal COVID-19 Vaccine Development
Using proprietary epitope prediction software to develop a better protective vaccine.
Universal Influenza Vaccine Project
Developing a broadly neutralizing flu vaccine to replace annual shots.
FAST Diagnostic Device for Low-resource Settings
Creating portable, sensitive nucleic acid detection tools for infectious diseases.
Research on influenza vaccine compositions published in US 20200129611.
Development of ultra IPV Vaccine for Polio
Progress towards IND enabling studies for a gamma radiation-inactivated Sabin-based polio vaccine.
Vaccine for Acinetobacter Baumannii
Finalization of a lead candidate using UVC inactivation tested at WRAIR.
Universal COVID-19 Vaccine Development
Using proprietary epitope prediction software to develop a better protective vaccine.
Universal Influenza Vaccine Project
Developing a broadly neutralizing flu vaccine to replace annual shots.
FAST Diagnostic Device for Low-resource Settings
Creating portable, sensitive nucleic acid detection tools for infectious diseases.
Research on influenza vaccine compositions published in US 20200129611.