BioAdvance


BioAdvance is an evergreen venture fund that invests in early-stage life-science companies, with a geographic focus on the Mid-Atlantic region. The firm describes a long-term investment perspective and reports that its portfolio companies have attracted over $4.2 billion of external capital.

BioAdvance

Philadelphia, Pennsylvania, United States, North America


Services

Early-stage equity investment

Provides capital to early-stage life-science companies.

Evergreen, long-term capital

Operates as an evergreen fund offering a long-term investment perspective.


Portfolio

Developed an RNAi molecule to treat macular degeneration. Merged into Opko Health, Inc. in 2007.

#RNA therapeutics / ophthalmology

Holds a platform exploiting protein-conformation dynamics to discover next-generation GPCR drugs aimed at reducing on-target side effects.

#GPCR drug discovery / therapeutics platform

Developed therapeutics and vaccines (CDX-110) against proprietary cancer targets; acquired by Celldex Therapeutics in 2005.

#Cancer therapeutics / vaccines

Company developing a novel approach to CDK4 inhibition intended to limit development of resistance seen with current therapies. Women-founded and run.

#Oncology / metastatic breast cancer therapeutics

Developed sensor-based technologies and a platform to improve medication adherence and care coordination in respiratory care.

#Digital health / respiratory care devices and platforms

Provides an allogeneic human TSC platform as a starting cell source for cell and gene therapy.

#Cell & gene therapy / allogeneic Trophoblast Stem Cell (TSC) platform

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