Berry Consultants LLC


Berry Consultants is a statistical consulting company specializing in innovative clinical trial design, analysis, implementation, and software solutions for the pharmaceutical and medical device industry. They focus on adaptive clinical trials and Bayesian analysis, aiming to improve the efficiency and effectiveness of clinical research.

Industries

biotechnology
clinical-trials
consulting
health-care
information-technology-dbca
medical-device
service-industry

Nr. of Employees

small (1-50)

Berry Consultants LLC


Products

Clinical trial simulation platform

A high-performance platform for simulating fixed and adaptive trial designs with engines for dose escalation, dose finding, adaptive phase 3, multiple endpoints, enrichment designs, and seamless phase 2/3 designs.

Adaptive design planning tool

An integrated planning tool for many adaptive designs including multiple comparison procedures, population enrichment, dose finding, and incorporation of MCPMod approaches with sample size and stopping-boundary calculations.

Development-program economic evaluation tool

A tool for quantifying and optimizing expected Net Present Value (eNPV) and Return on Investment (ROI) of a drug development program based on proposed clinical development plans.


Services

Consulting to design adaptive trials across phases (I–IV), including protocol development, simulation, and operating-characteristic evaluation.

Design and implementation support for multi-arm platform trials, including shared-control setup, infrastructure planning, and long-term protocol strategy.

Custom Bayesian analyses, prior elicitation, hierarchical modeling, comparative effectiveness evaluations, and decision analyses for development planning.

Simulation studies to evaluate trial performance, justify adaptive rules, and explore development strategies using specialized simulation platforms.

Licensing and customization of simulation and planning tools, plus technical support for integration into design workflows.

Provision of interim analysis services and participation on Data Monitoring Committees for adaptive and confirmatory trials.

View All Services

Expertise Areas

  • Adaptive clinical trial design
  • Platform/master-protocol trials
  • Bayesian statistics and hierarchical modeling
  • Clinical trial simulation and software
  • Show More (5)

Key Technologies

  • Bayesian hierarchical modeling
  • Adaptive design methods (response-adaptive randomization, arm dropping, enrichment)
  • Clinical trial simulation platforms
  • Model-based dose-escalation methods (CRM, Bayesian logistic regression)
  • Show More (4)

News & Updates

A 6-week public webinar series on 'Case Studies in using FACTS to design Clinical Trials'.

A podcast summarizing a recent paper on Lecanemab for patients with early Alzheimer Disease, highlighting the benefits of adaptive clinical trial design.


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