Baseline Bioscience


Developer of a handheld saliva-based diagnostic platform for rapid point-of-care assessment of neurological conditions and traumatic brain injury. Activities described on the site include saliva sample collection device design, quantitative lateral-flow assay development, salivary biomarker R&D (proteins and nucleic acids), preparatory clinical study planning, and an associated intellectual-property portfolio.

Industries

biotechnology

Nr. of Employees

small (1-50)

Baseline Bioscience

Irvine, California, United States, North America


Patents

Assay device, system, method, and kit

US-11112405-B1

View Details

Products

Handheld saliva rapid assessment device

A handheld saliva collection and testing platform using a disposable absorption pad/wick and lateral-flow test strips to detect disease-specific biomarkers with rapid visual or reader-assisted results.


Services

R&D and development of salivary biomarker assays for detection of neurodegenerative disease and TBI, including selection and validation of marker panels and lateral-flow implementation.

Design and coordination of clinical studies to validate saliva-based diagnostic devices and biomarkers for regulatory submission.

Executive and commercial advisory services related to market positioning, partnership development, and product launch strategies for diagnostic technologies.

Expertise Areas

  • Salivary diagnostics
  • Quantitative lateral-flow assay development
  • Saliva nucleic acid (microRNA) assays
  • Pre-analytical standardization for oral fluid studies
  • Show More (4)

Key Technologies

  • Quantitative lateral-flow immunoassays
  • Saliva collection devices (absorption pads and transfer mechanisms)
  • Salivary microRNA detection
  • Antibody-based capture assays
  • Show More (3)

News & Updates

Review of quantitative lateral-flow methods and their application to salivary biomarkers.

Technical paper discussing biochemical approaches to analyzing oral fluids for biomarkers.

Blog post discussing the need for accurate saliva-based diagnostics and examples of diseases under investigation.

Article describing regulatory guidance on early Alzheimer’s disease and the role of biomarkers as surrogate endpoints; outlines focus on saliva-sourced biomarkers.

Overview of saliva as a diagnostic medium and its advantages for non-invasive testing and home collection.

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