Atea Pharmaceuticals, Inc.


Atea Pharmaceuticals is a clinical-stage biopharmaceutical company dedicated to discovering, developing, and commercializing oral antiviral therapies to address unmet medical needs in viral diseases, including hepatitis C and COVID-19. The company leverages its expertise in antiviral drug development, medicinal chemistry, biology, biochemistry, and virology to create innovative treatments with the potential to transform patient care.

Industries

biopharma
biotechnology
health-care
pharmaceutical

Nr. of Employees

medium (51-250)

Atea Pharmaceuticals, Inc.

225 Franklin Street, Suite 2100, Boston, MA 02110


Patents

Highly active compounds against COVID-19

US-12226429-B2

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β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment

US-12084473-B2

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Nucleotide hemi-sulfate salt for the treatment of hepatitis c virus

US-12006340-B2

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2′-substituted-N6-substituted purine nucleotides for RNA virus treatment

US-11975016-B2

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Highly active compounds against COVID-19

US-11813278-B2

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Highly active compounds against COVID-19

US-11738038-B2

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Products

Oral combination regimen of a nucleotide analog polymerase inhibitor and an NS5A inhibitor for hepatitis C

An oral two-drug regimen combining a nucleotide analog polymerase inhibitor and an NS5A inhibitor designed as a pan-genotypic, once-daily treatment for hepatitis C virus (HCV); demonstrated high sustained virologic response in Phase 2 and advanced to global Phase 3 development.


Services

End-to-end internal capabilities for discovering, optimizing and advancing oral small-molecule antivirals, including medicinal chemistry, preclinical studies, CMC and clinical development.

Strategic collaborations and licensing arrangements to develop, distribute and commercialize investigational antiviral therapies.

Expertise Areas

  • Clinical trial management (Phase 1–3)
  • Antiviral drug discovery and development
  • Medicinal chemistry of nucleoside/nucleotide prodrugs
  • Purine nucleotide prodrug development
  • Show More (6)

Key Technologies

  • Purine nucleotide prodrug chemistry
  • Nucleoside/nucleotide analogs
  • Viral RNA-dependent RNA polymerase inhibition
  • In vitro replicon assays
  • Show More (6)

News & Updates

Update on financial results and business progress, including ongoing clinical trials and collaborations.

Full results from a Phase 2 study demonstrating 98% SVR12 rate after 8 weeks of treatment with bemnifosbuvir and ruzasvir.

Panel discussion on current challenges in HCV treatment and the potential of Atea's therapies.

Partnership to develop and commercialize AT-527, an antiviral candidate, for COVID-19 treatment.

Appointment of industry veteran to the company's board to support development of antiviral therapies.

New appointments to leadership team to support late-stage development of antiviral candidates.

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