Antirna, Inc.


Small biotech startup based in Burlington, MA focused on small-molecule antiviral discovery. Primary R&D emphasis is on inhibitors of S-adenosylmethionine (SAM)-dependent methylation reactions involved in viral mRNA capping, with particular attention to coronaviruses and COVID-19. The organization reports expertise in virology, virus culture and optimization, and development of broad-spectrum respiratory antiviral candidates.

Industries

N/A


Products

Carbocyclic nucleoside antiviral candidate (broad‑spectrum, preclinical)

A lead compound class of carbocyclic nucleoside analogues developed as broad‑spectrum antivirals against respiratory viruses, with a development focus including SARS‑CoV‑2/COVID‑19.

Expertise Areas

  • Small-molecule antiviral discovery
  • Antiviral mechanism targeting mRNA capping methylation
  • Carbocyclic nucleoside chemistry
  • Virology and viral culture
  • Show More (2)

Key Technologies

  • Small-molecule medicinal chemistry
  • Carbocyclic nucleoside synthesis
  • Viral culture and assay systems
  • Methyltransferase inhibition (SAM-dependent)
  • Show More (1)

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