Antabio


Antabio is a privately-held clinical-stage biopharmaceutical company dedicated to developing novel and highly differentiated antibacterial treatments for drug-resistant infections caused by WHO and CDC critical priority pathogens. The company focuses on life-threatening respiratory infections, including carbapenem-resistant nosocomial pneumonia and chronic pulmonary diseases. With an international team of experts and a strong track record of attracting non-dilutive funding, Antabio aims to address urgent unmet medical needs in the antibacterial space.

Industries

biotechnology
life-science
medical-device

Nr. of Employees

small (1-50)

Antabio

436 Rue Pierre et Marie Curie, 31670 Labège, France


Patents

Indane derivatives for use in the treatment of bacterial infection

US-12286411-B2

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Indane derivatives for use in the treatment of bacterial infection

US-12247013-B2

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Diazabicyclooctanones as inhibitors of serine beta-lactamases

US-11905286-B2

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Chemical compounds

US-11299467-B2

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Chemical compounds as antibiotics

US-11000511-B2

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Antibacterial thiazolecarboxylic acids

US-9914712-B2

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Products

Intravenous carbapenem plus serine β-lactamase inhibitor combination for severe hospital Gram-negative infections

A β-lactam/β-lactamase inhibitor combination developed to restore carbapenem activity against carbapenem-resistant Enterobacterales, carbapenem-resistant Acinetobacter baumannii and other priority Gram-negative pathogens; developed through clinical trials for hospital-acquired infections including nosocomial pneumonia.

Inhaled elastase inhibitor for Pseudomonas aeruginosa respiratory infections

Nebuliser-administered inhaled small-molecule inhibitor targeting Pseudomonas elastase to reduce virulence and support treatment of chronic respiratory infections such as cystic fibrosis, bronchiectasis and COPD.

Metallo-β-lactamase inhibitor to restore carbapenem activity against NDM-producing strains

A small-molecule metallo-β-lactamase inhibitor developed to potentiate carbapenem antibiotics against NDM-positive Enterobacterales and similar resistant pathogens (preclinical and publication-supported program).

Expertise Areas

  • Antibacterial drug discovery and development
  • β-lactamase inhibitor discovery (serine and metallo classes)
  • Clinical development of anti-infectives (early-phase)
  • Inhalation therapeutics and nebulised delivery
  • Show More (6)

Key Technologies

  • Serine β-lactamase inhibition
  • Metallo β-lactamase inhibition
  • Combination β-lactam + β-lactamase inhibitor therapy
  • Inhalation/nebuliser drug delivery
  • Show More (6)

News & Updates

The positive Phase 1 data supports further patient studies of MEM-ANT3310, a novel antibacterial candidate targeting drug-resistant pathogens.

Dr. Erick Lelouche has been appointed as Chairman of the Board of Directors at Antabio.

Led by the AMR Action Fund, the financing will support the clinical development of MEM-ANT3310 up to Phase 2 trials.

The trial for MEM-ANT3310, targeting severe hospital infections, has begun with initial dosing.

Led by Antabio, ARPEGE is funded by the French government to develop strategies against antimicrobial resistance.

Funding to support the development of MEM-ANT3310, a broad-spectrum therapy targeting WHO’s priority pathogens.

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