Anavex Life Sciences Corp.


Anavex Life Sciences Corp. is a biopharmaceutical company dedicated to the development of targeted CNS treatments for diseases such as Alzheimer’s, Parkinson’s, Rett syndrome, and other neurodegenerative and neurodevelopmental disorders. The company focuses on innovative therapeutics, including small molecule treatments targeting the Sigma-1 receptor, with a mission to improve patients' lives through scientific discovery and community engagement.

Industries

biopharma
biotechnology
health-care
manufacturing
therapeutics

Nr. of Employees

small (1-50)

Anavex Life Sciences Corp.

630 5th Avenue, 20th floor, New York, NY 10111 USA


Patents

A2-73 as a therapeutic for insomnia, anxiety and agitation

US-12285403-B2

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Sigma-1 receptor agonist systolic blood pressure therapy

US-12280034-B2

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Enantiomers of A2-73, analogues, and sigma agonist activity

US-12208079-B2

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A2-73 crystalline polymorph compositions of matter and methods of use thereof

US-12180174-B2

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Treatment of cardiac dysfunction

US-12138240-B2

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Analgesic therapeutic and method, 1-(3-4(((1R,3S,5S)-adamantan-1-yl)(phenyl)methyl)propyl)-4-methylpiperazine and salts thereof

US-11896590-B2

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Products

Investigational orally available SIGMAR1-activating small molecule (investigational)

An investigational, orally administered small-molecule therapeutic designed to activate an upstream compensatory receptor pathway with the aim of restoring cellular homeostasis and enhancing autophagy in CNS disorders; currently in clinical development.


Services

End-to-end clinical program support including protocol design, medical monitoring, study execution, TMF oversight, and coordination with CROs and vendors.

Statistical design and analysis services including SAP development, sample size calculation, programming for derived datasets, and review/validation of tables, figures and listings.

Design and oversight of RWE and pharmacoepidemiology studies to generate evidence from EMR, registries and claims for regulatory, payor, and clinical decision support.

Preclinical and translational experiments to characterize drug mechanism(s), including assays related to autophagy and neuronal homeostasis.

Preparation of regulatory documents, interaction with health authorities, and support for designation requests and risk-management planning.

Expertise Areas

  • Clinical trial management
  • Biostatistics and statistical programming
  • Epidemiology and real-world evidence (RWE)
  • Clinical operations and TMF management
  • Show More (8)

Key Technologies

  • Orally available small-molecule therapeutics
  • Receptor modulation for CNS (SIGMAR1 modulation implied)
  • Autophagy modulation assays and models
  • Preclinical in vivo models
  • Show More (4)

News & Updates

Company participation in upcoming healthcare conferences to share progress and insights.

Company reports financial results and updates on business activities.

Research on Blarcamesine's potential to improve autophagy in Alzheimer’s disease.


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