Alkeus Pharmaceuticals, Inc.
Alkeus Pharmaceuticals is dedicated to preserving the sight of individuals impacted by retinal diseases. They focus on developing therapies for serious eye diseases with high unmet needs, including Stargardt disease and geographic atrophy secondary to age-related macular degeneration. Their lead candidate, gildeuretinol (ALK-001), is a novel therapy designed to reduce vitamin A dimerization, which is associated with retinal damage and vision loss. The company is engaged in multiple clinical trials and has received various designations from the FDA to support their development efforts.
Industries
Nr. of Employees
small (1-50)
Alkeus Pharmaceuticals, Inc.
Products
Oral deuterated vitamin A analog for retinal degenerative disease
A once-daily oral small-molecule deuterated analog of vitamin A designed to reduce vitamin A dimer formation in the retina, evaluated in clinical trials for inherited Stargardt disease and geographic atrophy secondary to age-related macular degeneration.
Oral deuterated vitamin A analog for retinal degenerative disease
A once-daily oral small-molecule deuterated analog of vitamin A designed to reduce vitamin A dimer formation in the retina, evaluated in clinical trials for inherited Stargardt disease and geographic atrophy secondary to age-related macular degeneration.
Services
Clinical development and regulatory strategy
In-house execution of clinical programs for retinal disease therapeutics, including trial design, regulatory interactions, and data dissemination.
Clinical development and regulatory strategy
In-house execution of clinical programs for retinal disease therapeutics, including trial design, regulatory interactions, and data dissemination.
Expertise Areas
- Clinical trial management (randomized, double-masked, placebo-controlled and open-label studies)
- Rare inherited retinal disease therapeutics
- Preclinical drug discovery and deuterated small-molecule chemistry
- Regulatory strategy and FDA accelerated programs
Key Technologies
- Deuterated small-molecule chemistry
- Oral small-molecule therapeutic formulation
- Fundus autofluorescence imaging (FAF)
- Microperimetry