ADvantage Therapeutics Inc.


ADvantage Therapeutics is dedicated to developing novel therapeutics for neurodegenerative conditions, with a major focus on Alzheimer’s Disease (AD). The company is currently approved for Phase 2 clinical trials in Europe and has an ILAP Passport designation from MHRA in the UK, which may allow for early commercialization after phase 2. With a research team at the Vienna BioCenter, ADvantage aims to create paradigm-changing therapies to treat AD and other aging-related diseases.

Industries

biotechnology
health-care
medical

Nr. of Employees

small (1-50)

ADvantage Therapeutics Inc.


Patents

Increasing gene expression

US-12134772-B2

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DNA binding proteins and uses thereof

US-11866469-B2

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Treatment and prevention of Alzheimer's disease (AD)

US-11857568-B2

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Compositions and methods for modulating gene expression

US-11807850-B2

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Treatment of Alzheimer's Disease (AD) with an aluminum salt

US-11147873-B2

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Treatment and prevention of alzheimer's disease (AD)

US-11065273-B2

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Products

Immunostimulant subcutaneous therapeutic candidate for early Alzheimer’s (clinical-stage)

A clinical-stage immunostimulant therapeutic candidate administered subcutaneously that demonstrated reduced hippocampal volume loss and slowed cognitive decline in a Phase 2 trial control arm; reported safety and tolerability in trial participants.


Services

End-to-end clinical development for neurodegenerative disease candidates, including protocol execution, patient enrollment, biomarker collection, and outcome analysis for Phase 2 studies.

Expertise Areas

  • Alzheimer’s disease therapeutics
  • Clinical trial management (Phase 2)
  • Immunology and immunotherapy development
  • Biomarker-driven clinical research and neuroimaging
  • Show More (4)

Key Technologies

  • Mimotope-based vaccine and immunostimulant approaches
  • Proteomics (clinical/translational)
  • MRI-based volumetric imaging (hippocampal volumetry)
  • Biomarker-enhanced clinical trial design
  • Show More (3)

News & Updates

Klothea Bio collaborates with Healthy Longevity Clinic, a top semifinalist in the $101 million XPRIZE Healthspan competition.

Advantage Therapeutics Inc. announces the formation of Klothea Bio, Inc. to advance research and development of Klotho protein for age-related therapeutics.

ADvantage Therapeutics welcomes Dr. William Haseltine as a strategic advisor to drive innovation.

AD04T™ is a therapeutic approach for modifying Alzheimer’s disease through modulation of hippocampal lipid metabolism.

The company announced breakthrough findings showing that AD04™ has immediate symptomatic and disease-modifying properties in Alzheimer’s disease treatment.

Dr. Makoto Kuro-o, discoverer of the Klotho gene and pioneer in longevity and disease prevention, joins the scientific advisory board.

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