Acurx Pharmaceuticals, Inc.


Acurx Pharmaceuticals is a publicly held clinical stage biopharmaceutical company focused on developing new antibiotics for difficult to treat infections. Their approach targets the DNA polymerase IIIC enzyme and their pipeline includes candidates targeting Gram-positive bacteria such as MRSA, VRE, and PRSP. The company is actively engaged in advancing its research and development efforts, with recent financial results and cash flow statements indicating ongoing operations and financing activities.

Industries

pharmaceutical

Nr. of Employees

small (1-50)

Acurx Pharmaceuticals, Inc.

White Plains, New York, United States, North America


Products

Clinical-stage DNA polymerase IIIC inhibitor (clinical candidate)

A clinical-stage small-molecule antibiotic candidate designed to inhibit bacterial DNA polymerase IIIC/PolC for treatment of Clostridioides difficile infection and other Gram-positive infections.

Early-stage Gram-positive antibiotic candidate portfolio

Pipeline of discovery-stage small-molecule antibiotic candidates directed at Gram-positive bacteria including MRSA, VRE and Streptococcus species.


Services

Collaborative preclinical and translational research

Sponsored research and collaborative agreements with academic and clinical partners to generate target validation, efficacy and microbiome data supporting development of antibiotic candidates.

Scientific communication and conference presentation support

Preparation and delivery of scientific posters, oral presentations and publications to communicate nonclinical and clinical study results to scientific and clinical audiences.

Expertise Areas

  • Enzyme-targeted antibiotic discovery
  • Preclinical microbiology and in vivo pharmacology against Gram-positive pathogens
  • Clinical trial management for anti-infectives (including Phase 2 randomized, double‑blind studies)
  • Microbiome sequencing and comparative analysis in drug development
  • Show More (6)

Key Technologies

  • Target-based small-molecule inhibitor discovery
  • In vitro antibacterial susceptibility assays
  • Preclinical animal infection models
  • Microbiome sequencing and comparative bioinformatics
  • Show More (4)

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