Acceligen


Acceligen is a pioneer in Precision Breeding, dedicated to addressing global challenges in animal health and food security. Their mission is to empower farmers and ranchers to provide safe, abundant food by cultivating healthier animals through sustainable practices. They focus on integrating advanced genetic insights and gene editing technologies to improve animal well-being, disease resistance, and sustainability, ultimately contributing to a more humane and efficient livestock industry.

Industries

animal-feed
biotechnology
health-care

Nr. of Employees

small (1-50)

Acceligen

Eagan, Minnesota, United States, North America


Patents

Materials and methods for producing animals with short hair

US-10716298-B2

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Methods for spermatogonial stem cell (SSC) transfer

US-9670458-B2

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Products

Heat tolerance trait (slick coat phenotype)

Genetic variant introduction to confer improved thermotolerance in cattle, intended to reduce heat stress and associated productivity losses in hot climates.

Polled (hornless) trait for cattle

Introduction of naturally occurring hornless alleles to eliminate the need for dehorning procedures.

PRRS resistance trait for swine

Genetic approaches aimed at producing pigs with reduced susceptibility to Porcine Reproductive and Respiratory Syndrome viruses.

Disease-resistance and parasite-resistance traits for aquaculture

Genetic development aimed at increasing disease resilience in farmed fish, including resistance to sea lice and other pathogens to reduce antibiotic use.

Gene-Edited

First gene-edited calf with reduced susceptibility to BVDV, a major viral pathogen affecting bovine health and well-being worldwide.

Gene-Edited Pigs with KISS1 Gene Modification

Gene editing targeting the KISS1 gene to potentially replace physical castration in pigs by controlling puberty onset.

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Services

Collaborative development and deployment of genetic traits for cattle, swine, and fish aimed at improving disease resistance, heat tolerance, welfare traits, and sustainability outcomes.

Stakeholder engagement and field studies with breeders, NGOs, and industry partners to select traits of commercial and welfare importance and validate their performance under production conditions.

Operational collaboration to combine genetic trait development with reproductive technologies to scale distribution of improved genetics.

Expertise Areas

  • Precision breeding and gene editing
  • Livestock and aquaculture trait development
  • Assisted reproductive technologies integration
  • Animal health and welfare genetics
  • Show More (6)

Key Technologies

  • CRISPR/Cas gene editing
  • Allele introgression / precision breeding
  • Assisted reproductive technologies (ART) for trait dissemination
  • Genomic selection and trait prioritization
  • Show More (2)

News & Updates

Growing demand for milk in Africa significantly boosts agricultural GDP in Ethiopia, Kenya and Tanzania.

Genome editing is the latest breeding tool capable of accelerating the rate of genetic improvement for health and well-being traits in food animals.

Findings highlight the potential of gene editing to reduce heat stress and improve productivity in cattle, especially in hot climates. This breakthrough represents a significant step towards more sustainable and humane livestock production.

The publication shows that Acceligen is meeting the challenge of uniquely breeding pigs resistant to PRRSV-1 and PRRSV-2.

PRRS is the most devastating disease to the swine industry in the United States, affecting productivity, health, and wellness of pigs, causing significant economic losses.

Acceligen, a Minnesota-based precision breeding business, edited to have shorter coats better suited to hotter temperatures, aiming to help livestock cope with climate change.

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