A-line, Inc.
ALine Inc. is a microfluidics company dedicated to providing expert engineered solutions for commercial-ready microfluidic products and devices. With over 50 years of industry experience, ISO 13485:2016 certification, and a focus on innovation, ALine designs, engineers, and manufactures microfluidic cartridges, manifolds, wearables, and other solutions for health, research, and industrial applications. The company emphasizes transparency, quality, and continuous improvement, supporting clients from research to large-scale manufacturing. Additionally, ALine is a key player in the Austin microfluidic industry, leveraging local innovation, academic collaborations, and advanced manufacturing techniques including 3D printing and microfabrication. The company is actively involved in developing microfluidic devices for biomedical diagnostics, drug development, environmental monitoring, and space applications, with a strong focus on rapid prototyping, scalable manufacturing, and integration of cutting-edge technologies like AI and advanced materials.
Industries
Nr. of Employees
small (1-50)
A-line, Inc.
Rancho Dominguez, California, United States, North America
Products
Modular breadboard instrumentation modules for cartridge integration
Hardware modules and electronics platforms providing pneumatic, pumping and thermal control for testing and iterating microfluidic cartridges during development.
Microfluidic consumable cartridges
Single-use microfluidic cartridges manufactured with integrated fluidics, reagent storage and membrane interfaces for diagnostic and life-science assays.
Custom 3D-printed fluidic connectors
Low-volume and scalable 3D-printed fluidic connectors tailored to device geometry to minimize dead volume and simplify external tubing interfaces.
Mechanically driven sequencing manifold (patented actuator)
Mechanically actuated sequencing manifold enabling low-power pneumatic sequencing of multistep fluid processes suitable for portable or resource-limited systems.
Modular breadboard instrumentation modules for cartridge integration
Hardware modules and electronics platforms providing pneumatic, pumping and thermal control for testing and iterating microfluidic cartridges during development.
Microfluidic consumable cartridges
Single-use microfluidic cartridges manufactured with integrated fluidics, reagent storage and membrane interfaces for diagnostic and life-science assays.
Custom 3D-printed fluidic connectors
Low-volume and scalable 3D-printed fluidic connectors tailored to device geometry to minimize dead volume and simplify external tubing interfaces.
Mechanically driven sequencing manifold (patented actuator)
Mechanically actuated sequencing manifold enabling low-power pneumatic sequencing of multistep fluid processes suitable for portable or resource-limited systems.
Services
Microfluidic device design and design-for-manufacture consulting
Consulting and engineering to develop microfluidic devices from concept through DfM-ready designs, executed as phased programs with documentation and risk management.
Rapid prototyping and pilot manufacturing
Prototype fabrication and low-to-mid volume manufacturing using laminate fabrication, CNC machining, die-cutting, 3D printing and cleanroom assembly; support for bridge manufacturing and transfer to volume partners.
Systems engineering and instrumentation integration
Development of modular test instrumentation and electronics to exercise and validate integrated cartridge and instrument subsystems including pneumatic, thermal and pumping control.
3D-printed connector design and fabrication
Custom 3D-printed fluidic connectors to minimize dead volume and provide compact chip-to-world interfaces tailored to device geometry.
Materials evaluation for organ-on-chip and diagnostic devices
Selection and evaluation of polymeric materials, hydrogels and thermoplastics for biocompatibility, optical properties and chemical resistance in organ-on-chip and diagnostic applications.
Microfluidic device design and design-for-manufacture consulting
Consulting and engineering to develop microfluidic devices from concept through DfM-ready designs, executed as phased programs with documentation and risk management.
Rapid prototyping and pilot manufacturing
Prototype fabrication and low-to-mid volume manufacturing using laminate fabrication, CNC machining, die-cutting, 3D printing and cleanroom assembly; support for bridge manufacturing and transfer to volume partners.
Systems engineering and instrumentation integration
Development of modular test instrumentation and electronics to exercise and validate integrated cartridge and instrument subsystems including pneumatic, thermal and pumping control.
3D-printed connector design and fabrication
Custom 3D-printed fluidic connectors to minimize dead volume and provide compact chip-to-world interfaces tailored to device geometry.
Materials evaluation for organ-on-chip and diagnostic devices
Selection and evaluation of polymeric materials, hydrogels and thermoplastics for biocompatibility, optical properties and chemical resistance in organ-on-chip and diagnostic applications.
Expertise Areas
- Microfluidic device architecture and phased product development
- Design for manufacture (DfM) and manufacturability assessment
- Rapid prototyping and additive manufacturing for fluidics
- Pilot and bridge manufacturing with injection molding scale-up
Key Technologies
- Laminate fluid-circuit fabrication
- Injection molding for microfluidics
- High-resolution 3D printing for fluidic components
- Die-cutting and laser processing for polymers