3N Bio


3N Bio is a life science start-up spun off from SciLifeLab/Karolinska Institutet, focusing on microbial metadegradomics to enhance the development of small molecules that modulate the microbiome. Their technology provides immediate information on the effect of new drug substances on the microbiome, aiming to speed up diagnosis of phenotypic antimicrobial resistance and improve patient outcomes. Their mission is to develop quick, simple tests for detecting antimicrobial resistance to enable fast diagnosis, personalized treatment, and rational antibiotic use.

Industries

Biopharma
Biotechnology
Genetics
Biotechnology Research

Nr. of Employees

small (1-50)

3N Bio

Stockholm, Stockholm County, Sweden


Products

Rapid culture-independent antimicrobial resistance diagnostic (in development)

A molecular diagnostic approach under development that uses bacterial mRNA degradation signatures to determine phenotypic response to antibiotics quickly from complex samples without culture or isolation.


Services

Partnerships and collaborative research to develop rapid, molecular diagnostics that infer bacterial growth and drug response from RNA decay signatures.

Expertise Areas

  • Phenotypic antimicrobial susceptibility testing
  • Culture-independent molecular diagnostics
  • mRNA translation and decay research
  • Microbiome–drug interaction studies
  • Show More (1)

Key Technologies

  • mRNA translation and decay analysis
  • RNA sequencing
  • Sequence-based profiling of RNA degradation patterns
  • Culture-independent molecular assays
  • Show More (2)

News & Updates

Extremely happy to see the scientific work on which 3N Bio is based published in Nature Microbiology. The article is titled 'Atlas of mRNA translation and decay for bacteria' by Huch, S., Nersisyan, L., et al.

The laboratory of co-founder Vicent Pelechano at Karolinska Institutet received a Proof-of-concept grant from the Swedish Research Council to develop a simplified antimicrobial resistance (AMR) diagnosis kit.

Fundamental research in metadegradomics received 9M SEK to demonstrate its applicability to study the interaction between antimicrobial resistance and the microbiome.


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