SR One

RNA targeting platform focused on genetic, cardiometabolic and central nervous system diseases

#Rare diseases

Whole-gene insertion technologies to enable a potential new class of genetic medicines

#Other

Innovative gene-based immuno-oncology treatments for solid tumors

#Oncology

Developing next generation TYK2 inhibitors for autoimmune diseases

#Immunology

Clinical stage biologic treatments for oncology and inflammatory diseases

#Immunology

Focused on targeting the Glucose-Dependent Insulinotropic Polypeptide (GIP) receptor to pioneer novel treatments for obesity and cardiometabolic diseases

#Cardiometabolic

Novel, adaptive, controllable cell therapies for the treatment of patients with cancer and autoimmune diseases

#Oncology

Developing an easy-to-use and needle-free epinephrine nasal spray to treat severe allergies

#Immunology

Novel, oral small molecule therapeutics for neurodegenerative diseases

#CNS

Developing inhaled therapies to treat rare respiratory diseases

#Other

Advancing a pipeline of potential best-in-class oncology therapies

#Oncology

A new class of small, chemically synthesized medicines for oncology and beyond

#Oncology

Leveraging Targeted Protein Degradation for novel therapeutics for oncology and inflammatory diseases

#Immunology

Developing therapeutics exploiting alternative RNA splicing

#Oncology

Transformative gene-based medicines for serious human diseases

#Rare diseases

New class of molecules for degenerative disorders

#Rare diseases

Platform for selective depletion of disease-causing cells in oncology and other diseases

#Immunology

Targeting extrachromosomal DNA to power the next wave of cancer treatments

#Oncology

Formulation technology making biologic therapies more accessible

#Other

Highly selective medicines for functionally and genomically defined cancer patients

#Oncology

Unlocking nature's regulatory mechanisms to fuel the discovery of new medicines

#Immunology

Developing therapies for rare ocular surface and retinal diseases

#Rare diseases

Developing a MDM2 inhibitor- Navtemadlin- for the treatment of myelofibrosis

#Oncology

Developing a candidate for a targeted approach to hypertension

#Cardiometabolic

Targeting the ubiquitin pathway with a new class of drugs

#CNS

Pioneering technologically-driven methods of drug discovery, to make therapeutics against the most challenging of targets

#Immunology

Improving upon the efficacy of cell therapy, making it more rapidly available to the broad population

#Oncology

A high-throughput proteomics platform to enable drug discovery

#Other

Focused on transforming lives of patients with immune dysfunctions and cancer

#Immunology

Extended half-life biologic treatments for psoriasis and other inflammatory diseases

#Immunology

Glyco-sensing molecules designed to overcome resistance to first-generation immuno-oncology drugs

#Immunology

Next-generation IgE targeting biologics for the treatment of food allergy and other allergic diseases

#Immunology

Advanced inhaled anti-infectives for targeted treatment of life-threatening lung infections

#Infectious Disease

Developing innovative therapeutics for renal diseases for Japanese and Asian patients

#Renal

Pioneering the integrated mapping of disease networks for precision therapeutics

#Oncology

Focused on orphan renal diseases

#Renal

Developing a novel IL-18 construct to treat oncology patients

#Oncology