Longitude Capital
Longitude Capital is a venture capital firm specializing in venture growth investments in biotechnology, medical technology, and health solutions companies. The firm focuses on improving clinical outcomes, enhancing patient quality of life, and reducing the cost of care. Since its inception in 2006, Longitude Capital has raised over $2 billion across six funds, demonstrating a strong track record in sourcing, managing, and exiting investments across various market cycles. The firm employs a balanced portfolio strategy, investing in clinical-stage and commercial-stage companies with clinically de-risked assets and favorable valuations. Longitude Capital leverages its extensive industry network and proprietary research to identify new investment opportunities and utilizes a variety of investment structures to optimize returns for stakeholders.
Longitude Capital
2740 Sand Hill Road, 2nd Floor, Menlo Park, CA 94025
What We Do
Longitude Capital works closely with portfolio companies to develop and implement strategic plans, achieve key operating objectives, and build world-class teams.
The firm assists portfolio companies in raising capital and pursuing liquidity opportunities to optimize returns for stakeholders.
Longitude Capital provides operational support to its portfolio companies, helping them achieve technical, clinical, and commercial milestones.
Investment Stage
Portfolio
Focused on nonalcoholic steatohepatitis (NASH) and other liver and metabolic disorders.
#Biotechnology
Developing treatments for Claudin-1 positive (CLDN1+) tumors and organ fibrosis.
#Biotechnology
Developing imaging and therapeutic molecules for the treatment of solid and hematologic cancers.
#Biotechnology
Developing the LOCOcyteTM cell-therapy platform for continuous local dosing of immunotherapeutics.
#Biotechnology
Developing novel therapies for obesity and metabolic diseases discovered by harnessing the biology of aging.
#Biotechnology
Developing a next-generation IVL (intravascular lithotripsy) device for the minimally invasive treatment of narrowed calcified arteries.
#Medical Technology
Provides solutions to transform utilization management for collaborative care journeys.
#Health Solutions
Provides holistic solutions for children with autism and other neurodevelopmental conditions.
#Health Solutions
Focused on the discovery and development of therapies to treat neurodegenerative diseases.
#Biotechnology
Developing therapeutics that promote mitochondrial biogenesis and function.
#Biotechnology
Developed a tech-enabled solution to meet the needs of nurses and healthcare provider organizations.
#Health Solutions
Commercializing a modernized Wearable Cardioverter Defibrillator.
#Medical Technology
Developing first-in-class monoclonal antibodies targeting the IL-11 receptor (IL-11R).
#Biotechnology
Developing a pipeline of gene therapies for rare and non-rare monogenic diseases.
#Biotechnology
Commercializing the Vivistim System, a novel vagus nerve stimulation (VNS) therapy.
#Medical Technology
Providing a digital platform to identify and manage obsessive-compulsive disorder.
#Health Solutions
Partners with primary care practices to provide clinical and administrative support.
#Health Solutions
Focused on discovering and developing small molecule inhibitors for cancer immunotherapy.
#Biotechnology
Developing pharmaceutical products for the treatment of brain tumors.
#Biotechnology
Developing a novel device for treating mitral valve regurgitation.
#Medical Technology
Creates products to detect microbial contamination in the manufacture of pharmaceuticals.
#Biotechnology
Providing concierge kidney care to delay or prevent the progression of chronic kidney disease.
#Health Solutions
Developing innovative cellular therapies for organ transplantation and severe auto-immune disorders.
#Biotechnology
Focused on developing treatments for immunological and inflammatory diseases.
#Biotechnology
Developing new treatments for patients suffering from serious diseases underserved by current therapies.
#Biotechnology
Delivering comprehensive care to medically frail seniors, resulting in better outcomes at lower cost.
#Health Solutions
Developing and commercializing unique therapies for patient populations in endocrinology, neurology, and gastroenterology.
#Biotechnology
Focused on developing a proprietary botulinum toxin complex for the treatment of multiple debilitating medical conditions.
#Biotechnology
Focused on delivering innovative therapies to patients with kidney disease.
#Biotechnology
Focused on the commercialization and development of therapeutics to improve cardiovascular health.
#Biotechnology
Intended to discover, design and develop novel biologics, protein and peptide therapeutics.
#Biotechnology
Developed helical anchor technology for improved endovascular aneurysm repair.
#Medical Technology
Developing next-generation immunomodulators with a proprietary High Affinity Ligands of Siglecs (HALOS™) nanotechnology platform to alleviate chronic, non-resolving inflammation.
#Biotechnology
Developing a miniaturized rechargeable implantable neuromodulation technology to treat urinary and fecal dysfunction.
#Medical Technology
Developing endoscopically-delivered devices for the treatment of obesity.
#Medical Technology
Developed and marketed Ofirmev, an intravenous form of acetaminophen for pain management.
#Biotechnology
Markets genomic tests to help cardiologists assess and treat cardiovascular disease.
#Biotechnology
Develops cancer immunotherapies designed to recognize and destroy tumor cells.
#Biotechnology
Developing CVT-301, a potentially transformative therapy for people with Parkinson’s disease.
#Biotechnology
Developing abuse-deterrent pharmaceutical products for chronic pain.
#Biotechnology
Developing pharmaceuticals for patients with severe metabolic and oncologic disorders.
#Biotechnology
Provides liquidity and financing solutions to royalty owners and companies in the global healthcare sector.
#Health Solutions
An orphan drug accelerator focused on identifying and de-risking programs with therapeutic and commercial potential.
#Biotechnology
Sells a virtually invisible, innovative hearing aid directly to the consumer.
#Medical Technology
Acquires and manages prescription dermatology assets for both cosmetic and medical procedures.
#Biotechnology
Developing oral, low-density, lipoprotein cholesterol (LDL-C) lowering therapies to treat hypercholesterolemia without statins.
#Biotechnology
Developing the Norm™ heart failure management system that enables patients to engage in physician directed self-management of heart failure.
#Medical Technology
Provides cellular services for both the fertility and cellular therapy sectors.
#Health Solutions
Developing the only pharmacologic treatment for infantile jaundice.
#Biotechnology
Developing a portfolio of NLRP3 inhibitors to treat inflammation driven diseases.
#Biotechnology
Developing and marketing specialty pharmaceuticals for a variety of neurological and oncologic conditions.
#Biotechnology
Developing NT-814 for the treatment of common, chronic debilitating female sex-hormone related conditions.
#Biotechnology
Developing a minimally-invasive technology for the treatment of chronic limb-threatening ischemia (CLTI).
#Medical Technology
Focused on the discovery, development and commercialization of next generation immunotoxins called Engineered Toxin Bodies for the treatment of cancer.
#Biotechnology
Developing tolperisone, a novel, patented skeletal muscle relaxant for the treatment of acute, painful muscle spasms without sedation.
#Biotechnology
Developed and markets the System One, a device for home-based nocturnal hemodialysis therapy.
#Medical Technology
Developed the world’s first electronically focusing progressive lens to move automatically between a user’s optimal near and far vision prescriptions.
#Medical Technology
Translating best-in-class gene engineering technologies into CAR T-cell immunotherapies for multiple myeloma, prostate and other cancers.
#Biotechnology
Provides a cloud-based electronic health record platform to connect doctors, patients and data to drive better health.
#Health Solutions
Markets diagnostic assays that help oncologists recommend chemotherapy regimens tailored to patients’ specific tumor genetics.
#Biotechnology
Developing surgical robotics to provide transformative solutions in urology.
#Medical Technology
Developed and marketed energy-based devices for a variety of aesthetic applications.
#Medical Technology
Developing a wearable, non-invasive medical device to reduce blood pressure in hypertensive patients.
#Medical Technology
Developing pan-variant tyrosine kinase inhibitors designed to overcome treatment-resistant cancer.
#Biotechnology
Focused on the development of therapies for patients with chronic kidney disease.
#Biotechnology
Developing pharmaceutical products for the treatment of overactive bladder and irritable bowel syndrome.
#Biotechnology
Developing devices to induce mild therapeutic hypothermia in heart attack and cardiac arrest patients.
#Medical Technology
Markets a suite of products for the reduction of facial wrinkles, rhytides and cellulite.
#Medical Technology
Key People
Managing Director
Managing Director
Managing Director
Managing Director
Managing Director and Chief Financial Officer
Managing Director
Managing Director
Managing Director
Associate
Associate
Vice President
Principal
Director of Investor Relations & Marketing
Senior Associate
Principal
Senior Analyst – Public Equities
Venture Partner
Vice President
Associate
Director of Operations & Facilities
Compliance and Legal Associate
Executive Assistant
Controller
Executive Assistant
Director of IT
VP of People
Vice President of Finance
Staff Accountant
IRM & Administrative Assistant
Head of Legal and Chief Compliance Officer
Executive Assistant
Senior Tax Manager
Executive Assistant