Physical Sciences Inc.
Physical Sciences Inc. (PSI) is an employee-owned company dedicated to inventing, demonstrating, and translating technologies that address critical national needs in defense, security, healthcare, and environmental stewardship. With over 50 years of experience, PSI combines extensive research and development capabilities with a commitment to innovation and customer focus.
Industries
N/A
Nr. of Employees
small (1-50)
Physical Sciences Inc.
20 New England Business Center, Andover, MA 01810
Patents
System and method for simultaneous high-sensitivity measurement of methane and ethane via laser absorption spectroscopy in an open-air configuration
2025-02-18 • US-12228501-B2
View DetailsCombined reflectance confocal microscopy-optical coherence tomography system for imaging of biological tissue
2017-05-23 • US-9655521-B2
View Details
System and method for simultaneous high-sensitivity measurement of methane and ethane via laser absorption spectroscopy in an open-air configuration
2025-02-18 • US-12228501-B2
View DetailsCombined reflectance confocal microscopy-optical coherence tomography system for imaging of biological tissue
2017-05-23 • US-9655521-B2
View DetailsProducts
Real-time lyophilization PAT monitoring system
Non-intrusive optical system providing continuous measurements of vapor mass flow and derived lyophilization process parameters to support cycle development and endpoint detection.
Multimodal skin imaging system (RCM + OCT)
Co-registered reflectance confocal microscopy and optical coherence tomography instrument for noninvasive assessment of skin morphology and lesion evaluation.
Handheld tissue-imaging probe for morphology analysis
Imaging probe combining OCT and RCM for micron-scale cross-sectional tissue imaging and automated morphological interpretation to support detection of disease-related changes such as cancer and fibrosis.
Adaptive-optics multimodal retinal imager
Retinal imaging system combining adaptive optics with multimodal imaging (confocal/offset apertures and AO-OCT) for cellular-level retinal morphology and functional assessment and capillary visualization without contrast agents.
Adaptive infrared imaging spectroradiometer
Infrared imaging spectroradiometer for standoff detection and characterization of vapors, aerosols and material signatures.
Compressive-sensing hyperspectral imager
Hyperspectral imager employing compressive-sensing techniques for high-speed LWIR scene analysis with reduced data throughput.
Real-time lyophilization PAT monitoring system
Non-intrusive optical system providing continuous measurements of vapor mass flow and derived lyophilization process parameters to support cycle development and endpoint detection.
Multimodal skin imaging system (RCM + OCT)
Co-registered reflectance confocal microscopy and optical coherence tomography instrument for noninvasive assessment of skin morphology and lesion evaluation.
Handheld tissue-imaging probe for morphology analysis
Imaging probe combining OCT and RCM for micron-scale cross-sectional tissue imaging and automated morphological interpretation to support detection of disease-related changes such as cancer and fibrosis.
Adaptive-optics multimodal retinal imager
Retinal imaging system combining adaptive optics with multimodal imaging (confocal/offset apertures and AO-OCT) for cellular-level retinal morphology and functional assessment and capillary visualization without contrast agents.
Adaptive infrared imaging spectroradiometer
Infrared imaging spectroradiometer for standoff detection and characterization of vapors, aerosols and material signatures.
Compressive-sensing hyperspectral imager
Hyperspectral imager employing compressive-sensing techniques for high-speed LWIR scene analysis with reduced data throughput.
Expertise Areas
- Optical sensing and imaging across UV–LWIR
- Hyperspectral and LIDAR remote sensing
- AI/ML for spectral analysis and sensor-data fusion
- CBRN detection systems and distributed sensor networks
Key Technologies
- Tunable diode laser absorption spectroscopy (TDLAS)
- Hyperspectral imaging (VNIR/SWIR/LWIR)
- Compressive sensing for imaging
- Spatial heterodyne spectroscopy
Key People
President and CEO
Chief Financial Officer
Chief Technology Officer
Executive Vice President, Material Systems
Executive Vice President, Optical Systems Division
President and CEO
Chief Financial Officer
Chief Technology Officer
Executive Vice President, Material Systems
Executive Vice President, Optical Systems Division
News & Updates
An upcoming event showcasing advancements in sensing technologies.
Announcement of new battery technology for space missions.
An upcoming event showcasing advancements in sensing technologies.
Announcement of new battery technology for space missions.