AvantGuard

AvantGuard has developed a novel broad-spectrum, bio-compatible antiseptic that is proven in in vitro, ex vivo, and in vivo testing to be safe and more effective than topical antibiotics, while also effective as a liquid sterilant or disinfectant. Our compound, Avantamine, can be packaged as a heat-tolerant, long-shelf-life powder in a metal foil packet that dissolves rapidly in potable water to make either a solution or hydrogel. At a high concentration, Avantamine's non-hazardous, non-corrosive solution will sterilize medical equipment in 10 minutes and is safe enough for instruments to be removed and used without rinsing. Diluted by half, Avant24 at 0.6% concentration is (1) an antiseptic for washing wounds or treating cutaneous bacterial and fungal infections, (2) a high-level disinfectant for a variety of medical devices without corroding metals or degrading plastics, and (3) a disinfectant for surfaces in the surgical suite. At 6X further dilution, Avant24 can treat trench mouth. At another 3X dilution, Avant24 can be added to water to make it drinkable. There are an enormous number of potential uses and the only difference between them is the amount of diluent, in this case water, used to prepare the solution. Our military focus areas are (1) low resource sterilization of medial devices, (2) fungal treatment for burn wounds, and (3) a prophylactic for infection control in a self-administered Role 1 environment with the powder applied directly to a wound. Our commercial focus area is Candida auris decolonization which is not currently possible with any other antiseptic. We have definitive animal testing to show efficacy and superiority to chlorhexidine and are moving toward the clinic.