Frontier Bio Corporation


Frontier Bio is a biotechnology company dedicated to creating lab-grown human tissues to replace animal studies, advance regenerative medicine, and develop engineered organs. Their mission is to revolutionize disease treatment and organ replacement through cutting-edge tissue engineering, with a vision of a future where organ donors are no longer needed and animal testing is a thing of the past.

Industries

biotechnology
manufacturing

Nr. of Employees

small (1-50)

Frontier Bio Corporation

3515 Breakwater Ave, Hayward, CA 94545


Patents

System and method for creating an object with a conduit with particular vascular applications

US-12435446-B2

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Employing human adipose-derived stem cells to propagate serum-derived hepatitis C virus and use thereof

US-10273461-B2

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Products

3D-bioprinted lung microtissue

Distal lung microtissue produced by 3D bioprinting combined with stem cell self-assembly, containing bronchioles, alveolar structures, vasculature, and functional features such as cilia, mucus, and surfactant.

Microfluidic blood–brain barrier chip

Organ-on-chip BBB platform that supports continuous barrier formation and neurovascular unit assembly for studies of transport, toxicity, and disease mechanisms.

Vascularized neural spheroids

Three-dimensional neural spheroids with integrated vasculature to improve nutrient/oxygen delivery and enhance functional readouts for screening and modeling.

Tissue-engineered blood vessels and aneurysm models

Living blood vessel constructs created by seeding cells onto biodegradable scaffolds and matured under biomimetic conditions; models include pathological geometries such as aneurysms for device testing.

Synthetic vascular simulation models (mechanical vessel mimics)

Non-living vessel simulants with mechanical and handling characteristics similar to native vessels for preclinical development and surgical rehearsal.


Services

Collaborative design and execution of research plans to develop human-relevant tissue models tailored to partner research questions.

Preclinical evaluation of vascular device deployment and tissue-device interactions using living engineered vessels and aneurysm models.

In vitro assays for drug transport, efficacy, and neurotoxicity using microfluidic BBB chips, vascularized neurospheres, and 3D lung microtissues.

Expertise Areas

  • Tissue engineering
  • 3D bioprinting
  • Organ-on-chip (blood–brain barrier) modeling
  • Vascular tissue engineering
  • Show More (4)

Key Technologies

  • 3D bioprinting
  • Stem cell differentiation and self-assembly
  • Microfluidics (organ-on-chip)
  • Biodegradable polymer scaffolds
  • Show More (3)

News & Updates

Frontier Bio announced a groundbreaking achievement in lab-grown lung tissue, combining 3D bioprinting with stem cell self-assembly to create complex microscale lung tissue, paving the way for advancements in treating respiratory diseases and organ transplantation.

Frontier Bio was recognized with a nomination for the 3D Printing Industry Awards 2024, highlighting its progress in healthcare innovation through 3D bioprinting.


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