CuriRx, Inc.
CuriRx, Inc. is a Massachusetts-based Contract Research, Development, and Manufacturing Organization (CRDMO) dedicated to redefining healthcare norms through innovative drug development solutions. The company emphasizes quality, agility, and responsibility, fostering a diverse and collaborative work environment. CuriRx offers a broad range of services including formulation, bioprocessing, analytical services, and support for complex biotherapeutic development, aiming to improve patient lives globally.
Industries
Nr. of Employees
small (1-50)
CuriRx, Inc.
Wilmington, Massachusetts, United States, North America
Products
High-resolution mass spectrometry CMC analytics platform
Laboratory platform centered on high-resolution mass spectrometry and orthogonal analytical techniques for characterization of complex biotherapeutics and CMC support.
High-resolution mass spectrometry CMC analytics platform
Laboratory platform centered on high-resolution mass spectrometry and orthogonal analytical techniques for characterization of complex biotherapeutics and CMC support.
Services
Formulation development
Laboratory development of drug formulations and dosage forms including prefilled syringes, lyophilized products, and nanotechnology-enabled formulations; formulation studies to support clinical and commercial development.
Bioprocessing development (upstream & downstream)
End-to-end cell culture and purification services including cell line development, media/feed optimization, bioreactor process development, chromatography and filtration development, viral clearance strategy, and scale-up support.
Analytical development and testing
Analytical method development, orthogonal characterization, phase-appropriate qualification and validation, and technology transfer to QC for both large and small molecule programs, from R&D through clinical release testing.
Quality testing and stability studies
ICH-aligned stability study design and execution, release testing, quantification and verification, and long-term stability data generation to support development and commercialization.
CMC analytical support using high-resolution MS
High-resolution mass spectrometry-based characterization services for product and process-related impurities, structural attributes, and targeted proteomics to de-risk CMC characterization.
Formulation development
Laboratory development of drug formulations and dosage forms including prefilled syringes, lyophilized products, and nanotechnology-enabled formulations; formulation studies to support clinical and commercial development.
Bioprocessing development (upstream & downstream)
End-to-end cell culture and purification services including cell line development, media/feed optimization, bioreactor process development, chromatography and filtration development, viral clearance strategy, and scale-up support.
Analytical development and testing
Analytical method development, orthogonal characterization, phase-appropriate qualification and validation, and technology transfer to QC for both large and small molecule programs, from R&D through clinical release testing.
Quality testing and stability studies
ICH-aligned stability study design and execution, release testing, quantification and verification, and long-term stability data generation to support development and commercialization.
CMC analytical support using high-resolution MS
High-resolution mass spectrometry-based characterization services for product and process-related impurities, structural attributes, and targeted proteomics to de-risk CMC characterization.
Expertise Areas
- Bioprocessing development
- Formulation development
- Analytical development and CMC characterization
- Cell line and strain development
Key Technologies
- High-resolution mass spectrometry
- LC-MS/MS peptide mapping
- HPLC / SEC-HPLC
- Bioreactor-based fed-batch and continuous culture