CritiTech Particle Engineering Solutions LLC


CritiTech and NanOlogy are innovative pharmaceutical companies specializing in particle engineering and drug delivery technologies. They develop proprietary submicron particle platforms for targeted, sustained delivery of chemotherapeutic agents, aiming to improve efficacy and safety in cancer treatment. Their technologies include Supercritical Precipitation and Purcision™, with applications in inhaled, intratumoral, and topical therapies. They collaborate with various clinical and research institutions to advance treatments for cancers such as pancreatic, lung, prostate, ovarian, and bladder cancers, as well as other serious diseases. Their mission is to transform systemic chemotherapy into local delivery methods that enhance tumor kill, elicit immune responses, and reduce systemic toxicity.

Industries

biotechnology
pharmaceutical

Nr. of Employees

small (1-50)

CritiTech Particle Engineering Solutions LLC

Lawrence, Kansas, United States, North America


Products

Supercritical fluid precipitation particle production platform

A continuous manufacturing platform that uses supercritical fluid-based processing to convert API crystals into stable, uncoated submicron particles intended for targeted, inhaled, or local delivery with prolonged tissue retention.

Spray-dried formulation and manufacturing capability

Spray drying service offering from proof-of-concept through cGMP production to create spray-dried API and excipient powders, including aerosols and powders for inhalation development.


Services

Pre-formulation and material characterization

Early-stage formulation design and material characterization to define target attributes and address solubility and delivery challenges.

Spray drying services (POC to cGMP)

Spray drying process development and manufacturing services, scalable from milligrams to hundreds of kilograms, including operations with organic solvents or water and handling of potent compounds.

Supercritical precipitation particle production and scale-up

Continuous supercritical fluid precipitation processing to produce stable, uncoated submicron particles intended to improve bioavailability, pharmacokinetics, and local retention.

Inhalation formulation and aerosol development

Design and development of inhaled therapies including nebulized suspensions and aerosol powders, supported by preclinical inhalation PK and efficacy studies.

Analytical services and particle characterization

Comprehensive analytical testing and in-house particle characterization to support formulation, release, and stability testing.

cGMP manufacturing, fill–finish and clinical supply

GMP production and fill–finish services including segregated cytotoxic and non-cytotoxic facilities to produce clinical and commercial batches.

View All Services

Expertise Areas

  • Particle engineering for poorly soluble drugs
  • Spray drying and aerosol powder manufacturing
  • Inhalation and pulmonary drug delivery
  • cGMP clinical and commercial manufacturing
  • Show More (6)

Key Technologies

  • Supercritical fluid precipitation for submicron particle formation
  • Spray drying (POC to cGMP)
  • Nebulized inhalation / nebulization delivery
  • Submicron / nanoparticle sterile suspension manufacturing
  • Show More (4)

Similar organizations

Browse all ORGANIZATIONS

JOIN OUR MAILING LIST

Stay Connected with MTEC

Keep up with active and upcoming solicitations, MTEC news and other valuable information.