Agenus Inc.


Agenus Inc. is dedicated to harnessing the power of the immune system to develop therapies with curative intent for individuals living with cancer. The company focuses on immuno-oncology (I-O) therapeutics, including antibody therapeutics, adoptive cell therapies, adjuvants, and vaccines, with a mission to expand the patient population benefiting from immunotherapy through innovative combination approaches.

Industries

biotechnology
medical
medical-device
therapeutics

Nr. of Employees

large (251-1000)

Agenus Inc.

3 Forbes Road, Lexington, MA 02421-7305


Patents

Anti-ILT4 antibodies and antigen-binding fragments

US-12344670-B2

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Anti-CTLA-4 antibodies and methods of use thereof

US-12246066-B2

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Anti-LAG-3 antibodies and methods of use thereof

US-12187795-B2

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Anti-TIM-3 antibodies and methods of use thereof

US-12011481-B2

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Anti-lag-3 antibodies and methods of use thereof

US-11993651-B2

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Antibodies and methods of use thereof

US-11993653-B2

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Products

Clinical-stage antibody therapeutic programs (immuno-oncology)

A portfolio of clinical-stage monoclonal antibody programs focused on immuno-oncology indications, including combination regimens evaluated in colorectal and ovarian cancers.

Adoptive cell therapy and vaccine/adjuvant programs

R&D-stage adoptive cell therapy programs and vaccine/adjuvant platforms developed via subsidiary operations or dedicated internal units.


Services

Provision of medical information, contact request handling, and support for investigator-sponsored clinical trials and access to investigational medicines.

Transfer of manufacturing assets and technology transfer activities to partner organizations to support biologics supply and scale-up.

Structuring of strategic collaborations, licensing arrangements and co-development partnerships to accelerate program development and provide commercial optionality.

Expertise Areas

  • Immuno-oncology antibody therapeutics
  • Antibody Fc engineering
  • Clinical trial management and execution
  • Neoadjuvant oncology development
  • Show More (4)

Key Technologies

  • Monoclonal antibody engineering
  • Fc-region (effector) engineering
  • CTLA-4 targeted immunotherapy
  • Combination immunotherapy regimens
  • Show More (4)

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